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Caspase-6, human recombinant protein

Catalog No.
E1006
Caspase-6, expressed in E. coli, suitable for cell culture.
Grouped product items
SizePriceStock Qty
25 units
$221.00
Ship with 10-15 days
100 units
$384.00
Ship with 10-15 days

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

Caspase-6 (also know as Mch2) belongs to the caspase-family of cysteine proteases. Like other caspases, caspase-6 exists in cells as an inactive proenzyme. Sequential activation of caspases plays a key role in the execution-phase of cell apoptosis. Caspases undergo proteolytic processing at conserved aspartic residues and produce two subunits, large (18 kDa) one and small (11 kDa) one. The two subunits dimerize to form the active enzyme. Active caspase-6 has been reported involving in the proteolysis of poly ADP-ribose polymerase (PARP), PARP is involved in DNA repair and henomic maintenance. The function of this protein in the caspase activation cascade is thought as a downstream enzyme and is processed by caspases 7, 8 and 10. Caspase-6 can also undergo self-processing without other caspases. The recombinant active human caspase-6 was expressed in E. coli.

Description

Gene ID: 839 Accession #: P55212
Alternate Names:Active Human Caspase-6, Active Caspase-6, Caspase-6 Enzyme, Recombinant caspase-6, human caspase-6, human caspases, active caspases.
Source: Escherichia Coli. M.Wt: (18 kDa) and small (11 kDa)
Appearance: Lyophilized powder Storage: Store at -70℃
Formulation:Lyophilized powder
Solubility:Reconstitute to 1 unit per μl in PBS containing 15% glycerol.
Shipping Condition: Gel pack. Handling: Centrifuge the vial prior to opening.
Usage:For Research Use Only! Not to be used in humans.

Quality Control

Quality Control & DataSheet

View current batch:
    Purity: ≥95%, by SDS-PAGE.
    Endotoxin Level:N/A