Signaling pathways
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BA3441 VerdiperstatSummary: Verdiperstat (AZD3241) is a selective, irreversible, orally available myeloperoxidase inhibitor. -
BA3442 PKUMDL-LC-101-D04Summary: PKUMDL-LC-101-D04 (GPX4-Activator-1d4) is a potent iron death regulator glutathione peroxidase 4 variant activator (=4.7). - BA3443 AZD5904Summary: AZD5904 is a selective and irreversible inhibitor of human myeloperoxidase.
- BA3444 PF-1355Summary: PF-1355 is a potent MPO inhibitor.
- BA3445 MitiperstatSummary: Mitiperstat (AZD4831) is a potent inhibitor of myeloperoxidase.
- BA3446 MPO-IN-28Summary: MPO-IN-28 is a myeloperoxidase inhibitor.
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BA3448 ML162-yneSummary: ML162-yne is a potent affinity probe for GPX4 inhibitors. - BA3449 MPO-IN-3Summary: MPO-IN-3 is a potent inhibitor (WO2013068875A1).
- BA3450 PF-06282999Summary: PF-06282999 is a potent, selective myeloperoxidase inhibitor.
- BA3451 MPO-IN-1Summary: MPO-IN-1 is a potent, orally active, irreversible myeloperoxidase inhibitor containing an indole structure with values of 2.6 μM and 5.3 μM for MPO and thyroid peroxides (TPO), respectively.