Signaling pathways
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BA3496 RIPA-56Summary: RIPA-56 is a highly selective and metabolically stable inhibitor of receptor-interacting protein 1. -
BA3497 GSK963Summary: GSK963 is a chiral, potent and selective inhibitor. -
BA3498 HS-1371Summary: HS-1371 is a highly efficient, ATP-competitive inhibitor. -
BA3500 EclitasertibSummary: Eclitasertib (DNL-758) is a receptor-interacting protein kinase 1 inhibitor. - BA3501 GSK3145095Summary: GSK3145095 is a kinase inhibitor.
- BA3504 PK68Summary: PK68 is a potent and specific type II inhibitor of receptor-interacting kinase 1 (RIPK1) with oral activity.
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BA3506 Necrostatin-34Summary: Necrostatin-34 (Nec-34) is an inhibitor of kinases. - BA3507 RIPK1-IN-4Summary: RIPK1-IN-4 is a potent inhibitor of type II kinase receptor-interacting protein 1 kinase.
- BA3508 OditrasertibSummary: Oditrasertib is a receptor-interacting protein kinase 1 inhibitor with values below 100 nM.
- BA3510 Zharp2-1Summary: Zharp2-1 is an orally potent RIPK2 inhibitor highly associated with inflammatory bowel disease (IBD).