Signaling pathways
-
BA2045 HalofuginoneSummary: Halofuginone (RU-19110), a derivative of Febrifugine, is a competitive inhibitor of prolyl-tRNA synthetase. - BA2046 RRx-001Summary: RRx-001 is a hypoxia-selective epigenetic factor used as a radiation or chemosensitizing agent that induces apoptosis and overcomes drug resistance in myeloma.
- BA2048 ObatoclaxSummary: Obatoclax (GX15-070), a BH3 mimetic, is a pan-family protein inhibitor.
- BA2049 DehydrocorydalineSummary: Dehydrocorydaline (13-Methylpalmatine) is an alkaloid.
- BA2051 WR99210Summary: WR99210 is an orally effective, low-toxicity dihydrofolate reductase inhibitor.
- BA2052 ML-SI3Summary: ML-SI3 is a mixture of cis/transML-SI3, a channel inhibitor.
- BA2054 ProguanilSummary: Proguanil is an antimalarial precursor that is metabolized to the active metabolite cyclic guanosine.
- BA2055 DDD85646Summary: DDD85646 (IMP-366) is an orally active inhibitor of N-myristoyltransferase from Trypanosoma brucei.
- BA2056 λ-CyhalothrinSummary: λ-Cyhalothrin is a highly effective broad-spectrum type II synthetic pyrethroid insecticide containing α-cyanide.
- BA2057 ParbendazoleSummary: Parbendazole is a potent inhibitor of recombination.