Signaling pathways
-
BA2039 MitoxantroneSummary: Mitoxantrone is a potent topoisomerase II inhibitor. -
BA2043 HydroxychloroquineSummary: Hydroxychloroquine (HCQ) is a synthetic oral antimalarial drug that is used in studies of malaria and autoimmune diseases such as systemic lupus erythematosus and rheumatoid arthritis. - BA2044 TPE-MISummary: TPE-MI (Tetraphenylethenemaleimide) is intrinsically non-fluorescent before binding to thiols via maleimide.
- BA2045 HalofuginoneSummary: Halofuginone (RU-19110), a derivative of Febrifugine, is a competitive inhibitor of prolyl-tRNA synthetase.
- BA2046 RRx-001Summary: RRx-001 is a hypoxia-selective epigenetic factor used as a radiation or chemosensitizing agent that induces apoptosis and overcomes drug resistance in myeloma.
- BA2048 ObatoclaxSummary: Obatoclax (GX15-070), a BH3 mimetic, is a pan-family protein inhibitor.
- BA2049 DehydrocorydalineSummary: Dehydrocorydaline (13-Methylpalmatine) is an alkaloid.
- BA2051 WR99210Summary: WR99210 is an orally effective, low-toxicity dihydrofolate reductase inhibitor.
- BA2052 ML-SI3Summary: ML-SI3 is a mixture of cis/transML-SI3, a channel inhibitor.
- BA2054 ProguanilSummary: Proguanil is an antimalarial precursor that is metabolized to the active metabolite cyclic guanosine.