Biochemical Reagent
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BA8431 PQM130Summary: PQM130, a brain-transmitting, weiroxone-donepezil hybrid compound, is a multi-targeted active molecule candidate for neurotoxicity induced by Aβ oligomers, and also possesses anti-inflammatory activity. - BA8432 RemternetugSummary: Remternetug is a human immunoglobulin G1-kappa, anti-APP (amyloid βA4 precursor protein) peptide monoclonal antibody.
- BA8433 RU-505Summary: RU-505 is a potent inhibitor of β-amyloid-fibrinogen interactions at 5.00 and 2.72 μM in fluorescence polarization (FP) and AlphaLISA assays, respectively.
- BA8434 MCAAD-3Summary: MCAAD-3 is a near-infrared Aβ imaging probe with blood-brain barrier penetration.
- BA8436 FSBSummary: FSB is a fluorescent dye.
- BA8437 MAO-B-IN-9Summary: MAO-B-IN-9 is a potent, selective, blood-brain barrier-crossing, irreversible, time-dependent inhibitor of (monoamine oxidase B).
- BA8438 LanabecestatSummary: Lanabecestat (AZD3293) is an orally active, blood-brain barrier-crossing inhibitor.
- BA8439 NB-360Summary: NB-360 is a potent, brain-penetrating
- BA8440 AtabecestatSummary: Atabecestat (JNJ-54861911) is a potent brain-permeable and orally active beta-site amyloid precursor protein cleaving enzyme 1 inhibitor that potently reduces reduced Aβ protein expression in cerebrospinal fluid.
- BA8441 BACE2-IN-1Summary: BACE2-IN-1 is a highly selective inhibitor with an inhibition constant of 1.6 nM.