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FXR (farnesoid X receptor) is a nuclear receptor that binds to hormone response elements on DNA, regulating the expression of certain genes when it is activated.

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  1. Cat.No. Product Name Information
  2. B1908 Chenodeoxycholic Acid Chenodeoxycholic Acid (CDCA), is a hydrophobic primary bile acid that activates nuclear receptors(FXR) involved in cholesterol metabolism.
  3. B1528 XL335 XL335 is a potent, selective and orally bioavailable agonist of the farnesoid X receptor (FXR) with EC50 value of 4 nM .
  4. B1527 GW4064 GW4064 is an agonist of FXR with EC50 values of 15nM and 90nM, respectively in an isolated receptor activity assay and in cells transfected with human FXR .
  5. B4888 Obeticholic Acid

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