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Potassium Channel

Potassium channels are voltage-gated ion channels that selectively permeate potassium ion through the excitable membrane. It regulates the release of neurotransmitters, insulin secretion, smooth muscle contraction and heart rate etc.

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  1. Cat.No. Product Name Information
  2. B2197 Nicorandil Nicorandil is potassium channel activator.Nicorandil is a vasodilatory drug used to treat angina.
  3. B2198 Nateglinide Nateglinide is an insulin secretagog agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM).
  4. B2195 Gliclazide Gliclazide is a sulfonylurea hypoglycemic agent used as an antidiabetic.
  5. B2194 Tolbutamide Tolbutamide is a potent inhibitor of cAMP with an IC50 value of 4mM .
  6. B2199 ML133 HCl

    ML133 is a selective potassium channel inhibitor for Kir2.1 with IC50 of 1.8 μM (pH 7.4) and 290 nM (pH 8.5), has no effect on Kir1.1 and weak activity for Kir4.1 and Kir7.1.

  7. B2196 Gliquidone Gliquidone is an ATP-sensitive K+ channel antagonist with IC50 of 27.2 nM.
  8. B1953 Indapamide Indapamide is a non-thiazide sulphonamide diuretic compound, generally used in the treatment of hypertension, as well as decompensated cardiac failure.
  9. B1289 Minoxidil Minoxidil is an antihypertensive vasodilator medication.
  10. B1935 Dronedarone HCl Dronedarone HCL is an amiodarone analogue which has been shown an effective and promising treatment for Atrial fibrillation (AF) .
  11. B2193 Mitiglinide Calcium Mitiglinide is a drug for the treatment of type 2 diabetes. It is a highly selective KATP channel antagonist.

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