P-gp

P-gp (P-glycoprotein) is a ATP-binding cassette transproters which overepxressed in multidrug-resistance cancer cells. It functions in pumping drug out of cell and lower intracellular drug concentration.

Compare Products

Product Name	P-gp
Tariquidar	****
Tariquidar methanesulfonate, hydrate	*
Zosuquidar	***
LY335979 (Zosuquidar 3HCL)	***
Dofequidar	*
Dofequidar fumarate	*

Cat.No. Product Name Information
A3956 Zosuquidar Zosuquidar (LY335979) is a potent modulator of P-glycoprotein-mediated multidrug resistance with Ki of 60 nM. Zosuquidar binds with high affinity to P-glycoprotein and inhibits P-glycoprotein-mediated multidrug resistance (MDR).
A3859 Tariquidar methanesulfonate, hydrate Tariquidar methanesulfonate, hydrate is a potent inhibitor of P-glycoprotein (Pgp), a 170-kDa transmembrane protein acting as a drug efflux pump to actively transport structurally unrelated compounds out of cell, which noncompetitively inhibits the basal the activity of ATPase associated with Pgp.
A8208 Tariquidar Tariquidar is a potent inhibitor of P-glycoprotein (Pgp), a 170-kDa transmembrane protein acting as a drug efflux pump to actively transport structurally unrelated compounds out of cells, that noncompetitively inhibits the basal the activity of ATPase associated with Pgp.
C3840 Estradiol 17-(β-D-Glucuronide) (sodium salt)
C3897 Estradiol 3-(β-D-Glucuronide) (sodium salt)
C3610 Hypophyllanthin
C3140 Rhodamine 123 (chloride)
A8549 LY335979 (Zosuquidar 3HCL)
LY335979 (Zosuquidar) is a selective Pgp (P-glycoprotein) inhibitor with a Ki of 59 nM.
B1167 Dofequidar fumarate Dofequidar fumarate is a multidrug-resistant (MDR) - reversal agent .
B1166 Dofequidar Dofequidar(MS-209) is a novel quinoline compound, which can reverse P-glycoprotein (P-gp)-mediated MDR.