Home >> Signaling Pathways >> Membrane Transporter/Ion Channel >> Kv1.3


Kv1.3 is a member of potassium voltage gated channel, shaker-related subfamily. It is required for T cell proliferation and activation.

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  2. A3699 PAP-1 PAP-1 is a selective inhibitor of Kv1.3, voltage-gated K+ channel. PAP-1 (EC50=2 nM) potently inhibits human T effector memory cell proliferation and delayed hypersensitivity.

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