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CRTH2

CRTh2 (chemoattractant receptor homologous molecule expressed on T-Helper type 2 cells ) is a G-protein coupled receptor for prostaglandin D2. Activation of CRTh2 increases the chemotaxis of Th2 cells/eosinophils/basophil, as well as eosinophil degranulation and Th2 cells cytokine release.

Biochemicals

  1. Cat.No. Product Name Information
  2. B1534 AZD1981 CRTh2 antagonist,potent and selective
  3. B4819 NVP-QAV680 potent and selective CRTh2 receptor antagonist