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DNA Damage/DNA Repair

  1. Cat.No. Product Name Information
  2. A8705 SCR7 DNA ligase IV inhibitor
  3. A8802 (S)-Crizotinib Potent MTH1 inhibitor
  4. B4935 SCH 51344 MTH1 inhibitor
  5. B5845 TH588 MTH1 inhibitor
  6. B5849 TH287 MTH1 inhibitor
  7. A4529 JW 55 Top Seller PARP domain inhibitor
  8. A4528 EB 47 Potent PARP-1 inhibitor
  9. A4527 DR 2313 PARP inhibitor
  10. A4526 BYK 49187 Potent PARP-1/PARP-2 inhibitor
  11. A4530 NU 1025 PARP inhibitor,potent and novel
  12. A4531 WIKI4 Inhibitor of Wnt/ß-Catenin signaling and tankyrase
  13. A8600 Tankyrase Inhibitors (TNKS) 22 Tankyrase inhibitor
  14. A8601 Tankyrase Inhibitors (TNKS) 49 Tankyrase inhibitor
  15. A8808 ME0328 PARP inhibitor,potent and selective
  16. B1163 MK-4827 hydrochloride PARP1/PARP2 inhibitor
  17. B1164 MK-4827 tosylate PARP1/PARP2 inhibitor
  18. A4525 BYK 204165 PARP-1 inhibitor,potent and selective
  19. A4524 4-HQN PARP inhibitor
  20. A3002 ABT-888 (Veliparib) Top Seller Potent PARP inhibitor
  21. A4154 Olaparib (AZD2281, Ku-0059436) Top Seller Potent PARP1/PARP2 inhibitor
  22. A4157 Iniparib (BSI-201) PARP1 inhibitor,intravenously adminsitered
  23. A4159 PJ34 hydrochloride Top Seller PARP inhibitor,potent and cell-permeable
  24. A4160 A-966492 PARP-1/-2 inhibitor, highly potent
  25. A4161 INO-1001 Potent PARP inhibitor
  26. A4163 UPF 1069 Selective PARP2 inhibitor
  27. A4164 AZD2461 Novel PARP inhibitor
  28. A3246 BMN-673 8R,9S PARP inhibitor
  29. A3617 MK-4827 PARP-1/-2 inhibitor,potent and selective
  30. A3729 PJ34 PARP-l inhibitor
  31. A3958 Veliparib dihydrochloride PARP-1/PARP-2 inhibitor
  32. B6086 BGP-15 PARP inhibitor
  33. A1877 XAV-939 Top Seller Tankyrase 1/2 inhibitor
  34. A4158 AG-14361 Potent PARP1 inhibitor
  35. A4156 Rucaparib (AG-014699,PF-01367338) Top Seller Potent PARP inhibitor
  36. A4153 BMN 673 Top Seller Potent PARP inhibitor
  37. B1383 VE-822 ATR inhibitor
  38. A8626 ETP-46464 ATR inhibitor,potent and selective
  39. A8625 CP-466722 ATM inhibitor,potent and reversible
  40. A8624 CGK733 ATM/ATR inhibitor,potent and selective
  41. A2521 VE-821 Top Seller ATR kinase inhibitor
  42. A3210 AZ20 ATR inhibitor,potent and selective
  43. A4605 KU 55933 Top Seller ATM inhibitor,potent and selective
  44. B6007 AZD6738 ATR inhibitor
  45. A8336 KU-60019 Top Seller ATM kinase inhibitor,potent and selective
  46. B1098 Altretamine hydrochloride Altretamine is an alkylating agent proposed as an antineoplastic.
  47. B1399 Temozolomide Temozolomide, an alkylating agent, is a DNA damage inducer.
  48. B1963 Lomustine Antineoplastic drug
  49. B3742 Thio-TEPA
  50. A2559 Altretamine Antineoplastic agent
  51. A8386 Busulfan DNA alkylating agent
  52. A3696 Palifosfamide Active metabolite of ifosfamide (IFOS)
  53. B3489 Carmustine
  54. B3927 Satraplatin
  55. B7426 L189 inhibitor of human DNA ligases I, III and IV
  56. A1912 Lomeguatrib Top Seller MGMT inhibitor
  57. A4176 Thioguanine Purine antimetabolite
  58. A8649 NU 7026 DNPK inhibitor,ATP-competitive and potent
  59. A1769 KU-0060648 Dual DNA-PK/PI3-K inhibitor, ATP-competitive
  60. A3352 Daun02 Cell viability inhibitor,DNA synthisis inhibitor
  61. A8315 NU7441 (KU-57788) Top Seller DNA-PK inhibitor
  62. B6945 DMNB New Product
  63. B7337 Compound 401 New Product
  64. A8646 Trovafloxacin mesylate Fluoroquinolone antibiotic
  65. A8647 Capecitabine chemotherapeutic agent
  66. A8648 Oxaliplatin Antitumor agent
  67. B1099 Daunorubicin DNA topoisomerase II inhibitor
  68. B1100 Cytarabine hydrochloride DNA synthsis inhibitor
  69. B1241 Marbofloxacin hydrochloride Marbofloxacin hydrochloride is a potent antibiotic of which depends upon its inhibition of DNA-gyrase.
  70. B1101 Mycophenolate mofetil hydrochloride Mycophenolate Mofetil is a non-competitive, selective and reversible inhibitor of inosine monophosphate dehydrogenase I/II with IC50 of 39 nM and 27 nM, respectively.
  71. B1892 Azathioprine Azathioprine(Azasan, Imuran) is a drug that suppresses the immune system and is used in organ transplantation and autoimmune disease.
  72. B3061 CRT0044876 APE1 inhibitor, potent and selective
  73. A8645 Viomycin Antibiotic of tuberactinomycin family
  74. A8644 Acyclovir Antiviral agent
  75. A8512 Rifaximin (Xifaxan) RNA synthesis inhibitor, PXR activator
  76. A3738 PSI-7977 Antiviral agents for chronic HCV infection
  77. A1412 Clofarabine Antimetabolite,inhibit DNA polymerase and ribonucleotide reductase
  78. A2343 Cyclophosphamide Nitrogen mustard alkylating agent and prodrug.
  79. A2548 Carmofur Cytostatic derivative of fluorouracilm,antineoplatic agent
  80. A2187 Cladribine Apoptosis inducer in CLL cells
  81. A2197 Dacarbazine Antineoplastic( malignant melanoma and sarcomas)
  82. A2097 Ifosfamide Cytostatic agent
  83. A1379 Nelarabine Prodrug of ara-G for T-LBL/T-ALL
  84. A8331 Bleomycin Sulfate Top Seller Chemotherapy agent, induces DNA strand break
  85. A8437 Gemcitabine inhibitor of DNA synthesis
  86. A8337 CX-5461 Top Seller Pol I-mediated rRNA synthesis inhibitor
  87. A8405 Cytarabine cytotoxic agent, blocks DNA synthesis
  88. B7336 Thiostrepton FOXM1 inhibitor
  89. B7587 Puromycin dihydrochloride analog of aminoacyl-tRNA
  90. B7667 8-Chloroadenosine New Product
  91. B4872 Mupirocin
  92. B4879 Blasticidin S HCl antibiotic, inhibits protein synthesis
  93. B4896 BMH-21 RNA polymerase I Inhibitior
  94. B5875 E3330 Inhibiting redox activity of APE1 protein.
  95. A8317 Fludarabine Phosphate (Fludara) Top Seller Inhibits STAT1 activation and DNA synthesis
  96. A5424 Fludarabine DNA synthsis inhibitor
  97. A3700 Paradol Active flavor constituent of the seeds of Guinea pepper
  98. A4546 Mithramycin A Anticancer antibiotic
  99. A4452 Mitomycin C Inhibits DNA synthesis,antibiotic and antitumor agent
  100. A2402 Floxuridine Antineoplastic antimetabolite
  101. A2171 Carboplatin Antitumor agent that forms platinum-DNA adducts.
  102. A1402 Gemcitabine HCl Top Seller Inhibits DNA synthesis,deoxycytidine analog
  103. A4071 Fluorouracil (Adrucil) Antitumor agent;inhibitor of thymidylate synthase
  104. A2451 Epirubicin HCl Antibiotic antitumor agent
  105. A1206 Daptomycin Calcium-dependent antibiotic
  106. A2355 Mercaptopurine (6-MP) Purine synthesis inhibitor
  107. B3209 Triapine Ribonucleotide reductase inhibitor
  108. B1476 Raltitrexed Raltitrexed (Tomudex, TDX, ZD 1694) is an antimetabolite drug used in cancer chemotherapy. It is an inhibitor of thymidylate synthase.
  109. B1471 Adenine HCl Adenine receptor agonist
  110. B1473 Uridine Uridine, Trisodium Salt is an energy-rich precursor in the enzymatic biosynthesis of RNA, a potent vasodilator, and induces contractile responses in some tissues.
  111. B1469 Adenine sulfate Sulfate salt form of adenine
  112. B1470 Procarbazine HCl Antineoplastic chemotherapy drug
  113. A3902 VAL-083 Bi-functional alkylating agent
  114. A4496 NSC 3852 HDAC inhibitor
  115. A4495 NCH 51 Histone deacetylase (HDAC) inhibitor
  116. A4493 KD 5170 HDAC inhibitor
  117. A3860 Tasquinimod Antiangiogenic and antineoplastic agent
  118. A3761 RG2833 Brain-penetrant HDAC inhibitor
  119. A3755 Resminostat hydrochloride HDAC inhibitor
  120. A3348 Daminozide KDM2A inhibitor
  121. A3305 CHAPS Zwitterionic detergent for membrane proteins,nondenaturing
  122. A4105 M344 Top Seller HDAC inhibitor,potent and cell-permeable
  123. A4104 AR-42 (OSU-HDAC42) Top Seller HDAC inhibitor,novel and potent
  124. A4497 Pyroxamide HDAC1 inhibitor
  125. A4499 TC-H 106 HDAC inhibitor
  126. A4498 SBHA HDAC1/HDAC3 inhibitor,cell-permeable
  127. B1251 Valproic acid HDAC1 inhibitor
  128. B1141 Varenicline Hydrochloride α4β2 nicotinic receptor agonist
  129. A8806 TMP269 HDAC 4/5/7/9 inhibitor
  130. A8803 RGFP966 Specific HDAC3 inhibitor
  131. A9906 HDAC Set I
  132. A8547 Tubastatin A HCl Top Seller HDAC6 inhibitor,potent and selective
  133. A4500 TCS HDAC6 20b Selective HDAC6 inhibitor
  134. A4494 LMK 235 HDAC4/HDAC5 inhibitor
  135. A4501 Tubacin HDAC6 inhibitor,potent,selective,reversible,cell-permeable
  136. A4103 LAQ824 (NVP-LAQ824,Dacinostat) HDAC inhibitor,potent and novel
  137. A4102 CI994 (Tacedinaline) Top Seller HDAC inhibitor
  138. A8171 Entinostat (MS-275,SNDX-275) Top Seller HDAC1 and HDAC3 inhibitor
  139. A4091 PCI-34051 HDAC8 inhibitor,potent and selective
  140. A4090 JNJ-26481585 Top Seller Potent HDAC inhibitor
  141. A4089 Mocetinostat (MGCD0103, MG0103) Top Seller HDAC inhibitor,isotype-selective and potent
  142. A4084 Vorinostat (SAHA, MK0683) Top Seller HDAC inhibitor
  143. A4083 Rocilinostat (ACY-1215) Top Seller Selective HDAC6 inhibitor
  144. N1315 Parthenolide Parthenolide is a sesquiterpene lactone and active principle of feverfew (Chrysanthemum parthenium)
  145. A8176 Apicidin Potent HDAC inhibitor
  146. A8173 Romidepsin (FK228, depsipeptide) Top Seller HDAC1/HDAC2 inhibitor,potent and selective
  147. A8183 Trichostatin A (TSA) Top Seller HDAC inhibitor
  148. A8178 Panobinostat (LBH589) Top Seller HDAC inhibitor
  149. A4092 CUDC-101 Multitargeted HDAC inhibitor
  150. A4093 ITF2357 (Givinostat) Top Seller HDAC inhibitor
  151. A4101 Tubastatin A HDAC6 inhibitor,potent and selective
  152. A4100 Droxinostat Selective HDAC inhibitor
  153. A4099 Valproic acid sodium salt (Sodium valproate) HDAC inhibitor
  154. A4098 PCI-24781 (CRA-024781) Pan-HDAC inhibitor
  155. A4097 CUDC-907 Potent PI3K/HDAC inhibitor
  156. A4096 Belinostat (PXD101) Hydroxamate-type HDAC inhibitor
  157. A4095 Pracinostat (SB939) Top Seller Pan-HDAC inhibitor
  158. A4094 MC1568 Top Seller Class II HDAC inhibitor,potent and
  159. A4108 Resminostat (RAS2410) Potent HDAC inhibitor
  160. A4107 Sodium Phenylbutyrate Histone deacetylase inhibitor
  161. A4106 Scriptaid Top Seller HDAC inhibitor,novel and cell-permeable
  162. B5882 ORY-1001 Selective inhibitor of KDM1A.
  163. B4988 BRD73954
  164. B4856 CAY10603
  165. B4794 Santacruzamate A (CAY10683) HDAC inhibitor, potent and selective
  166. B1147 Orotic acid Orotic acid (OA) is an intermediate in pyrimidine metabolism.
  167. B1877 Adenosine Adenosine is a nucleoside composed of a molecule of adenine attached to a ribose sugar molecule (ribofuranose) moiety via a β-N9-glycosidic bond.
  168. B1923 Cytidine Cytidine is a nucleoside molecule that is formed when cytosine is attached to a ribose ring, cytidine is a component of RNA.
  169. B1468 Adenine Adenine is a purine derivative and a nucleobase with a variety of roles in biochemistry.
  170. B1809 Penciclovir HSV-1 DNA synthesis inhibitor
  171. B2221 Zidovudine Reverse transcriptase inhibitor
  172. B1474 FT-207 (NSC 148958) Tegafur (also known as Ftorafur) is a chemotherapeutic 5-FU prodrug used in the treatment of cancers; is a component of tegafur-uracil.
  173. B1039 LY2334737 Anticancer agent
  174. A3139 Abacavir Inhibitor of HIV reverse transcriptase
  175. A2852 Leflunomide AHR agonist,immunosuppressive agent
  176. B4960 Penciclovir Sodium
  177. B5828 RX-3117 a cytidine analog and a substrate for uridine-cytidine-kinase
  178. B6080 Methylthioadenosine sulfur-containing nucleoside
  179. B3589 5-BrdU Synthetic thymidine analog
  180. A1945 BIBR 1532 Telomerase inhibitor,novel and selective
  181. A3327 Costunolide Apoptosis inducer
  182. B7627 TMPyP4 tosylate New Product
  183. B6009 6-Thio-dG telomere disrupting compound
  184. A2306 Ellagic acid Casein kinase 2 (CK2) inhibitor
  185. A1971 Etoposide Topo II inhibitor
  186. A2476 Idarubicin HCl Anthracycline and daunorubicin analog,topoisomerase inhibitor
  187. A2782 Amonafide DNA intercalator,Topo II inhibitor
  188. A5133 Irinotecan Topoisomerase I inhibitor
  189. A1602 Dexrazoxane HCl (ICRF-187, ADR-529) Topoisomerase II inhibitor,intracellular ion chelator,cardioprotective agent
  190. A5323 Moxifloxacin HCl Fluoroquinolone antibiotic
  191. A5511 Ofloxacin Fluoroquinolones,antibiotics
  192. A8532 Teniposide Teniposide is a glycoside-derivative of podophyllotoxin.
  193. A1832 Doxorubicin (Adriamycin) HCl Antitumour antibiotic,inhibits TOPO II.
  194. A2198 Genistein AR agonist
  195. A1313 Gatifloxacin Fluoroquinolone antibiotic,inhibits bacterial TOPO II
  196. A2877 Camptothecin Topoisomerase I inhibitor,prototypic
  197. A3123 4'-Demethylepipodophyllotoxin Anti-cancer drug
  198. A3355 Deferasirox Fe3+ chelate Oral iron chelator
  199. A3372 DOXO-EMCH Prodrug of doxorubicin
  200. A3434 Genz-644282 Non-camptothecin inhibitor of topoisomerase I
  201. A3872 TH-302 Hypoxia-activated prodrug,inhibits H460/HT29 cell growth

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