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5-HT Receptor

5-HT receptor (5-hydroxytryptamine receptors) is a group of GPCRs (G protein-coupled receptors) and LGICs (ligand-gated ion channels) found in the central and peripheral nervous systems.

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Biochemicals

  1. Cat.No. Product Name Information
  2. B2237 Eletriptan HBr Eletriptan hydrobromide is a orally active, selective 5-HT1B/1D receptor agonist.
  3. B2236 Desvenlafaxine Desvenlafaxine is a serotonin (5-HT) and norepinephrine (NE) reuptake inhibitor with Ki of 40.2 nM and 558.4 nM, respectively.
  4. B2246 Desvenlafaxine Succinate Desvenlafaxine Succinate is a new serotonin (5-HT) transporter and norepinephrine (NE) transporter reuptake inhibitor with Ki of 40.2 nM and 558.4 nM respectively.
  5. B2250 LY310762 LY310762 is a 5-HT1D receptor antagonist with Ki of 249 nM, having a weaker affinity for 5-HT1B receptor.
  6. B2253 Prucalopride 5-HT4A and 5-HT4B receptor agonist
  7. B2255 SB271046 5-HT6 receptor antagonist, orally active
  8. B2259 VUF 10166 VUF10166 is a novel, potent and competitive antagonist for 5-HT3A receptor with Ki of 0.04 nM, its affinity at 5-HT3AB receptor is significantly lower.
  9. B2260 WAY-100635 Maleate 5-HT1A receptor agonist
  10. B2233 Azasetron HCl 5-HT3 receptor antagonist
  11. B2243 Almotriptan Malate 5-HT1B/1D-receptor agonist
  12. B2241 Ondansetron Ondansetron(GR38032) is a serotonin 5-HT3 receptor antagonist used mainly as anantiemetic (to treat nausea and vomiting), often following chemotherapy.
  13. B2230 Trazodone HCl Antidepressant
  14. B2234 Clomipramine HCl SERT/NET dopamine transporter (DAT) blocker
  15. B2263 BMY 7378 5-HT1A partial agonist and α1D adrenoceptor antagonist
  16. B2231 Amitriptyline HCl Serotonin /norepinephrine receptor/5-HT4/5-HT2 inhibitor
  17. B2229 Palonosetron HCl Palonosetron Hcl is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV).
  18. B1754 Fenspiride HCl Fenspiride Hcl is an α adrenergic and H1 histamine receptor antagonist.
  19. B1204 Ondansetron hydrochloride dihydrate Ondansetron is a serotonin 5-HT3 receptor antagonist used mainly as anantiemetic (to treat nausea and vomiting), often following chemotherapy.
  20. B1002 Tropisetron Hydrochloride Tropisetron is a selective 5-HT3 receptor antagonist and α7-nicotinic receptor agonist with an IC50 of 70.1 ± 0.9 nM for 5-HT3 receptor.
  21. B1477 Lurasidone HCl Dopamine D2/5-HT2A/5-HT7/5-HT1A inhibitor
  22. B2258 Tropisetron Tropisetron(SDZ-ICS 930) is a selective 5-HT3 receptor antagonist and α7-nicotinic receptor agonist with an IC50 of 70.1 ± 0.9 nM for 5-HT3 receptor.
  23. B1205 Fluvoxamine serotonin reuptake inhibitor and σ₁ receptor agonist
  24. B1206 Pizotifen Pizotifen(Pizotyline) is a highly selective 5-HT receptor blocking agent, which is a benzocycloheptane based drug.
  25. B2007 Pizotifen Malate Pizotifen malate is a highly selective 5-HT receptor blocking agent, which is a benzocycloheptane based drug.
  26. B1059 Mosapride Mosapride is a gastroprokinetic agent that acts as a selective 5HT4 agonist.
  27. B2251 Naratriptan Naratriptan hydrochloride is a selective 5-HT1 receptor subtype agonist and is a triptan drug that is used for the treatment of migraine headaches.
  28. B2261 Zolmitriptan Zolmitriptan, a selective serotonin receptor agonist, is used to treat migraine attacks with or without aura and cluster headaches.
  29. B2242 Urapidil HCl Urapidil HCl is an α1-adrenoceptor antagonist and 5-HT1A receptor agonist.
  30. B2264 Dapoxetine HCl Selective serotonin reuptake inhibitor
  31. B2248 Ketanserin Selective 5-HT2A serotonin receptor antagonist; can also be used to discriminate between 5-HT1D and 5-HT1B receptor subtypes.
  32. B6736 Citalopram hydrobromide New Product
  33. B6799 Indatraline hydrochloride New Product
  34. B6851 Zimelidine dihydrochloride New Product
  35. B6852 S 14506 hydrochloride New Product
  36. B6883 Ipsapirone New Product
  37. B6952 Paroxetine maleate New Product
  38. B6954 (±)-McN 5652 5-HT uptake inhibitor
  39. B7097 Lofepramine New Product
  40. B5292 BTS 54-505 hydrochloride Potent SNRI,sibutramine metabolite
  41. B5406 NAD 299 hydrochloride New Product
  42. B5538 WY 45233 succinate New Product
  43. B5324 Dexfenfluramine hydrochloride New Product
  44. B6659 (S)-WAY 100135 dihydrochloride 5-HT1A receptor antagonist,potent and selective
  45. B6588 (R)-(+)-8-Hydroxy-DPAT hydrobromide New Product
  46. B6292 MDL 73005EF hydrochloride New Product
  47. B6293 MDL 72832 hydrochloride ligand for 5-HT1A receptor, potent and selective
  48. B6337 8-Hydroxy-DPAT hydrobromide New Product
  49. B6349 NAN-190 hydrobromide New Product
  50. B6351 BP 554 maleate Selective 5-HT1A agonist
  51. B6388 CGS 12066B dimaleate New Product
  52. B6410 Anpirtoline hydrochloride New Product
  53. B6457 8-Hydroxy-PIPAT oxalate New Product
  54. B6496 5-Nonyloxytryptamine oxalate New Product
  55. B6511 MM 77 dihydrochloride New Product
  56. B6537 Isamoltane hemifumarate New Product
  57. B6538 Cyanopindolol hemifumarate New Product
  58. B5366 (±)-MDMA hydrochloride New Product
  59. B1203 Iloperidone hydrochloride Iloperidone (hydrochloride) is a D(2)/5-HT(2) receptor antagonistis, which is an atypical antipsychotic for the treatment of schizophrenia symptoms.
  60. A3144 Adoprazine 5-HT1A receptor agonist and full D2/3 receptor antagonist
  61. A3796 SB-269970 5-HT7 receptor antagonist
  62. A3811 SEA0400 Specific inhibitor of Na+/Ca2+ exchange
  63. A3873 Tianeptine 5-HT facilitator
  64. A3918 Vilazodone Combined SSRI and 5-HT1A receptor partial agonist
  65. A3919 Vilazodone Hydrochloride Combined SSRI and 5-HT1A receptor partial agonist
  66. A3926 Vortioxetine 5-HT receptors antagonist
  67. A3933 WAY-100635 5-HT1A receptor antagonist,potent and selective
  68. A3934 WAY-100635 maleate salt 5-hydroxytryptamine1A antagonist
  69. A3952 Ziprasidone 5-HT (serotonin)/dopamine receptor antagonist
  70. A3953 Ziprasidone hydrochloride monohydrate 5-HT (serotonin)/dopamine receptor antagonist
  71. A1295 Granisetron HCl 5-HT3 receptor antagonist
  72. A1334 Mosapride Citrate 5-HT receptor agonist
  73. A3778 RS 127445 5-HT2B receptor antagonist,high affinity
  74. A3697 Palonosetron 5-HT3 antagonist
  75. A3157 Alosetron 5-HT3 receptor antagonist
  76. A3158 Alosetron (Z)-2-butenedioate 5-HT3 receptor antagonist
  77. A3159 Alosetron Hydrochloride 5-HT3 receptor antagonist,potent and highly selective
  78. A3160 Alosetron Hydrochloride(1:X) 5-HT3 receptor antagonist
  79. A3192 Asenapine hydrochloride Atypical antipsychotic
  80. A3239 B-HT 920 D2 receptor agonist
  81. A3241 Bilobalide Neuroprotective agent
  82. A3317 Clozapine N-oxide (CNO) Metabolite of clozapine, used in chemogenetics.
  83. A3330 CP-809101 5-HT2C receptor agonist
  84. A3331 CP-809101 hydrochloride 5-HT2C receptor agonist, potent and selective
  85. A3443 Granisetron Serotonin 5-HT3 receptor antagonist
  86. A3569 LY 344864 5-HT1F receptor agonist,potent and selective
  87. A5010 Asenapine Inhibits adrenergic receptor/5-HT receptor
  88. A2436 Fluoxetine HCl Serotonin reuptake inhibitor,selective
  89. A2553 Fluvoxamine maleate Serotonin reuptake inhibitor,selective,antidepressant
  90. B1198 Cisapride Cisapride(R 51619) is a nonselective 5-HT4 receptor agonist, it is also a potent human ether-à-go-go-related gene (hERG) potassium channel inhibitor.
  91. B2256 SB742457 5-HT6 receptor antagonist,highly selective and high affinity
  92. B2240 Olanzapine 5-HT2A/D2 antagonist
  93. B1199 Tandospirone Anxiolytic and antidepressant reagent
  94. B1058 Lasmiditan 5-HT1F receptor agonist
  95. B2239 Lorcaserin HCl selective full agonist of human 5-HT2C receptor with Ki of 15 nM.
  96. B2254 SB269970 HCl 5-HT7 receptor antagonist,potent and selective
  97. B1200 PRX-08066 5-HT2BR antagonist
  98. B2262 Agomelatine MT1/MT2 / 5-HT2C agonist
  99. B1201 Agomelatine hydrochloride Agomelatine is a competitive antagonist of human and porcine serotonin (5-HT2C) receptors (pKi = 6.2 and 6.4, respectively) as well as human 5-HT2B receptors (pKi = 6.6).
  100. B1202 Agomelatine L(+)-Tartaric acid Agomelatine (L(+)-Tartaric acid) is a antidepressant, which is classified as a norepinephrine-dopamine disinhibitor (NDDI) due to its antagonism of the 5-HT2C receptor.
  101. B1001 Loxapine 5-HT Receptor antagonist
  102. B2245 BRL-54443 5-HT1E/1F receptor agonist,potent and selective
  103. B2265 BRL-15572 5-HT1D receptor antagonist
  104. B1197 Risperidone mesylate Risperidone mesylate(R 64 766 mesylate) is a serotonin 5-HT2 receptor blocker(Ki= 0.16 nM) and a potent dopamine D2 receptor antagonist(Ki= 1.4 nM).
  105. A5355 Venlafaxine Dual serotonin/noradrenalin re-uptake inhibitor
  106. A5322 Tianeptine sodium 5-HT uptake facilitator,selective,antidepressant
  107. A5294 Sumatriptan Succinate 5-HT1 receptor agonist
  108. A5350 Ziprasidone HCl Serotonin and dopamine receptor antagonist
  109. A5399 Iloperidone Dopamine (D2) and serotonin (5HT2) receptor antagonist
  110. A2547 Vortioxetine (Lu AA21004) HBr 5-HT receptor modulator, antidepressant and anxiolytic
  111. A2098 PRX-08066 Maleic acid 5-HT2B receptor antagonist,potent and selective
  112. A8514 Risperidone SR-2A inhibitor
  113. A8516 Rizatriptan Benzoate Rizatriptan Benzoate is a selective serotonin 5-HTID receptor agonist which is structurally derived from tryptamine.
  114. A8384 Blonanserin Atypical antipsychotic
  115. A8421 Duloxetine HCl Duloxetine HCl is a selective serotonin and norepinephrine reuptake inhibitor .
  116. B1196 Risperidone hydrochloride Risperidone Hcl(R 64 766 Hcl) is a serotonin 5-HT2 receptor blocker(Ki= 0.16 nM) and a potent dopamine D2 receptor antagonist(Ki= 1.4 nM).
  117. A5166 Ondansetron HCl 5-HT3 receptor antagonist
  118. A3793 SB 271046 hydrochloride Selective 5-HT6 antagonist
  119. A3777 Rotigotine hydrochloride Agonist of dopamine D2/D3 receptor
  120. A3776 Rotigotine Agonist of dopamine D2/D3 receptor
  121. A3748 rac-Rotigotine Hydrochloride Agonist of dopamine D2/D3 receptor
  122. A3561 Lu AE58054 Hydrochloride 5-HT(6)R antagonist
  123. A3560 Lu AE58054 5-HT(6)R antagonist
  124. B4981 Sumatriptan 5-HT1 receptor agonist