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Autophagy

Autophagy is a catabolic process which degrades and recycles long-lived proteins and cytoplasmic organelles through lysosome. It plays an important role in growth regulation and maintenance of homeostasis.

5 Items

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  1. SAR405
    A8883 SAR405
     22 Citation
    Summary: Selective ATP-competitive inhibitor of Vps34
      ≥22.19 mg/mL
  2. LY3009120
    A8716 LY3009120
    Target: Raf
    Summary: pan-RAF and RAF dimer inhibitor
      insoluble in H2O; insoluble in EtOH; ≥4.25 mg/mL
  3. Spautin-1
    B5873 Spautin-1
     1 Citation
    Target: Deubiquitinating enzymes (DUBs)|Autophagy
    Summary: Novel autophagy inhibitor
      insoluble in H2O; ≥13.5 mg/mL
  4. STF-62247
    B2151 STF-62247
    Target: Autophagy
    Summary: Autophagy inducer in renal cell
  5. Rocilinostat (ACY-1215)
    A4083 Rocilinostat (ACY-1215)
     1 Citation
    Target: Histone Deacetylases (HDACs)
    Summary: Selective HDAC6 inhibitor
      ≥21.675 mg/mL

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