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VEGFR

VEGFR are receptors for vascular endothelial growth factor and belong to receptor tyrosine kinases.

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  1. Fruquintinib(HMPL-013)
    B5864 Fruquintinib(HMPL-013)
    Target: VEGFR
    Summary: Potent and selective inhibitor of VEGFR 1, 2, 3
      insoluble in H2O; insoluble in EtOH; ≥6.35 mg/mL
  2. Dovitinib (TKI258) Lactate
    B5953 Dovitinib (TKI258) Lactate
    Target: CSF-1R|FLT3|VEGFR|PDGFR|c-Kit|FGFR
    Summary: Oral tyrosine kinase inhibitor (TKI) against FGFR1–3, VEGFR1–3, and platelet-derived growth factor receptor (PDGFR).
      insoluble in EtOH; ≥10.62 mg/mL
  3. MAZ51
    C3342 MAZ51
    Target: VEGFR
    Summary: VEGFR3 antagonist
      insoluble in EtOH; insoluble in H2O; ≥31.4 mg/mL
  4. Sorafenib
    A3009 Sorafenib
     2 Citation
    Target: Raf|VEGFR
    Summary: Raf kinases and tyrosine kinases inhibitor
      ≥23.25 mg/mL
  5. Pazopanib (GW-786034)
    A3022 Pazopanib (GW-786034)
    Target: CSF-1R|VEGFR|PDGFR|c-Kit|FGFR
    Summary: VEGFR/PDGFR/FGFR inhibitor
      insoluble in EtOH; insoluble in H2O; ≥10.95 mg/mL
  6. Regorafenib hydrochloride
    A3750 Regorafenib hydrochloride
    Target: Raf|VEGFR|PDGFR|c-Kit|c-RET
    Summary: Tyrosine kinase inhibitor
      ≥25.95 mg/mL
  7. SU 5402
    A3843 SU 5402
    Target: VEGFR|PDGFR|FGFR
    Summary: VEGFR2/FGFR/PDGFR/EGFR inhibitor
      insoluble in EtOH; insoluble in H2O; ≥14.8 mg/mL
  8. SU5416
    A3847 SU5416
    Target: VEGFR
    Summary: VEGF receptor inhibitor and AHR agonist
      insoluble in EtOH; insoluble in H2O; ≥11.9 mg/mL
  9. TG 100801
    A3870 TG 100801
    Target: VEGFR|FGFR|Src|Fyn kinase
    Summary: Multi-kinase inhibitor
      Soluble in DMSO

Items 21-29 of 29

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