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FGFR

FGFRs (fibroblast growth factor receptors) are transmembrane tyrosine kinase receptor. It is involved in carcinogenesis and plays an important role in cell differentiation, survival and proliferation etc.

4 Items

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  1. Nintedanib (BIBF 1120)
    A8252 Nintedanib (BIBF 1120)
     3 Citation
    Target: VEGFR|PDGFR|FGFR
    Summary: VEGFR/PDGFR/FGFR inhibitor
      insoluble in H2O; insoluble in EtOH; ≥5.34 mg/mL
  2. Dovitinib (TKI-258, CHIR-258)
    A2168 Dovitinib (TKI-258, CHIR-258)
     2 Citation
    Target: FLT3|VEGFR|PDGFR|c-Kit|FGFR
    Summary: Multitargeted RTK inhibitor
      insoluble in H2O; insoluble in EtOH; ≥36.35 mg/mL
  3. AZD4547
    A8350 AZD4547
    Target: FGFR
    Summary: FGFR inhibitor
      ≥23.2 mg/mL
  4. ACTB-1003
    B4904 ACTB-1003
    Target: VEGFR|FGFR|Tie-2|RSK|p70 S6K
    Summary: FGFR1 inhibitor
      insoluble in H2O; ≥18.15 mg/mL

4 Items

per page