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ALK

ALK (anaplastic lymphoma kinase) is a member of insulin receptor protein-tyrosine superfamily, functioning in embryonic development and involved in cell survival and cell fate.

9 Items

per page
  1. PF-06463922
    B4882 PF-06463922
    Target: ALK|ROS1
    Summary: ALK/ROS1 inhibitor,potent and selective
      insoluble in H2O; ≥20.3 mg/mL
  2. Entrectinib
    B5859 Entrectinib
    Target: Trk Receptors|ALK|ROS1
    Summary: Orally active inhibitor of ALK kinase
      ≥28.05 mg/mL
  3. DMH-1
    B3686 DMH-1
    Target: BMP and Other Activin Receptors
    Summary: Selective BMP ALK2 receptor
      insoluble in H2O; insoluble in EtOH; ≥9.51 mg/mL
  4. ML347
    B3688 ML347
    Target: BMP and Other Activin Receptors
    Summary: BMP receptor inhibitor,potent and selective
      insoluble in H2O; insoluble in EtOH; ≥5.87 mg/mL
  5. SB525334
    A5602 SB525334
    Summary: (TGF-beta1) receptor inhibitor
      ≥34.3 mg/mL
  6. LDN-193189
    A8324 LDN-193189
    Target: BMP and Other Activin Receptors
    Summary: ALK inhibitor,potent and selective
      insoluble in DMSO; insoluble in EtOH; insoluble in H2O
  7. CH5424802
    A8393 CH5424802
    Target: ALK
    Summary: ALK inhibitor,potent and ATP-competitive
  8. AZD-3463
    A8620 AZD-3463
     3 Citation
    Target: ALK|Insulin-like growth factors (IGFs)
    Summary: ALK/IGF1R inhibitor
      insoluble in H2O; insoluble in EtOH; ≥11.22 mg/mL
  9. (R)-Crizotinib
    A3020 (R)-Crizotinib
     2 Citation
    Target: c-MET
    Summary: C-MET/ALK inhibitor,potent and ATP-competitve
      insoluble in H2O; insoluble in EtOH; ≥7.51 mg/mL

9 Items

per page