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PKC

PKC (protein kinase C) is a serine/threonine protein kinase that mediates insulin signaling, actin cytoskeleton, cell mobility, apoptosis and tumorigenesis etc.

Items 41-49 of 49

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  1. K-252c
    A8344 K-252c
    Target: PKC|PKA
    Summary: Protein kinase inhibitor
      insoluble in EtOH; insoluble in H2O; ≥15.55 mg/mL
  2. Go 6983
    A8343 Go 6983
     1 Citation
    Summary: pan-PKC inhibitor
      ≥22.15 mg/mL
  3. GF 109203X
    A8342 GF 109203X
     1 Citation
    Target: PKC
    Summary: Protein kinase C,MLCK,PKG and PKA inhibitor
      insoluble in EtOH; insoluble in H2O; ≥20.6 mg/mL
  4. Go 6976
    A8341 Go 6976
    Target: PKC
    Summary: PKCα/PKCβ1 inhibitor
      ≥15.77 mg/mL
  5. Zoledronic Acid
    A1352 Zoledronic Acid
    Target: Farnesyl Diphosphate Synthases
    Summary: Potent nitrogen-containing bisphosphonates
      insoluble in DMSO; insoluble in H2O; insoluble in EtOH
  6. Enzastaurin (LY317615)
    A1670 Enzastaurin (LY317615)
     2 Citation
    Target: PKC
    Summary: PKC beta inhibitor,potent and selective
      insoluble in EtOH; insoluble in H2O; ≥8.59 mg/mL
  7. Chelerythrine Chloride
    A3306 Chelerythrine Chloride
    Target: PKC
    Summary: PKC antagonist
      insoluble in H2O; ≥19.2 mg/mL
  8. (-)-Epigallocatechin gallate (EGCG)
    A2600 (-)-Epigallocatechin gallate (EGCG)
    Target: BACE
    Summary: Antioxidant, antiangiogenic and antitumor agent
      ≥22.9 mg/mL
  9. Staurosporine
    A8192 Staurosporine
     6 Citation
    Summary: Protein kinase inhibitor,potent and cell permeable
      insoluble in H2O; insoluble in EtOH; ≥11.66 mg/mL

Items 41-49 of 49

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Relate Categories
Category
  • Bcr-Abl 17items
  • PKC 49items
  • Pyk2 3items
  • ROCK 16items
  • SMAD 6items
  • TAK1 1item
  • TGF-βR1(ALK5) 14items
Specificity
  1. Selective 7 items
Reversibility
  1. Reversible 1 item
Target
  1. PKC 10 items
  2. Ca2 /calmodulin-dependent protein kinases (CaMKs) 1 item
  3. PKA 2 items
  4. Farnesyl Diphosphate Synthases 1 item
  5. PRAK 1 item
  6. MAPKAP-K2 1 item
  7. Calcium-Activated Potassium (KCa) Channels 1 item
  8. BACE 1 item
  9. KDR 1 item
  10. Flk1 1 item
  11. PPK 1 item
  12. c-Syk 1 item
  13. CDK1/CyclinB 1 item
Reported Experiments
  1. Animal Experiments 13 items
  2. Cell Experiments 11 items
Related Disease
  1. Adrenocortical Carcinoma 1 item
  2. Breast Cancer 2 items
  3. Cancer 8 items
  4. Colon Cancer 1 item
  5. Glioblastoma 1 item
  6. Leukemia 2 items
  7. Lymphoma 1 item
  8. Pancreatic Cancer 2 items
  9. Prostate Cancer 1 item