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Signaling Pathways
Neuroscience
Dopamine Receptor

Dopamine Receptor

Dopamine receptors (DR) are members of G protein-coupled receptors superfamily. There are 5 subtypes (D1, D2, D3, D4, D5) of DR which mediate the functions of dopamine in central nervous system for control of locomotion, cognition, and emotion etc.

B1242 Haloperidol hydrochloride

Summary: Antipsychotic drug

insoluble in H2O; ≥10.31 mg/mL
B2235 Clozapine

Target: 5-HT2 Receptors|D1 and D5 Receptors|D2 Receptors|D3 Receptors|5-HT1 Receptors|D4 Receptors

Summary: 5-HT receptor antagonist

insoluble in H2O; ≥14.95 mg/mL
B1479 Amisulpride

Summary: Dopamine D2/D3 receptor antagonist
B2232 Aripiprazole

Target: 5-HT1 Receptors

Summary: 5-HT receptor partial agonist

≥22.4 mg/mL
B1102 Brexpiprazole

Summary: 5-HT2A, α1B-, and α2C-adrenergic receptors antagonist

≥21.68 mg/mL
B1626 LY404039

Summary: MGlu2 and mGlu3 receptors agonist

insoluble in DMSO; insoluble in EtOH; insoluble in H2O
B1490 Quetiapine Fumarate
1 Citation

Target: 5-HT2 Receptors|D1 and D5 Receptors|D2 Receptors|D3 Receptors|5-HT1 Receptors|5-HT7 Receptors

Summary: Dopamine receptor antagonist

insoluble in H2O; insoluble in EtOH; ≥11.03 mg/mL
B1485 Pergolide mesylate

Target: D1 and D5 Receptors|D2 Receptors

Summary: Dopaminergic agonist

insoluble in EtOH; insoluble in H2O; ≥6.84 mg/mL
B1486 Amantadine HCl

Summary: Dopamine receptor agonist
B1488 Pramipexole

Target: D2 Receptors|D3 Receptors|D4 Receptors

Summary: Dopamine agonist

insoluble in H2O; ≥10.57 mg/mL