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HCV

HCV (hepatitis C virus ) is a enveloped single-stranded RNA virus of the Flavivridae family. It lead to acute hepatitis, chronic liver disease and liver cancer.

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  1. Daclatasvir (BMS-790052)
    A5618 Daclatasvir (BMS-790052)
    Target: HCV Proteases
    Summary: HCV NS5A inhibitor
      ≥36.6 mg/mL
  2. T 705
    B1114 T 705
    Target: RNA Polymerases
    Summary: Potent and selective RNA-dependent RNA polymerase inhibitor
      ≥2.9 mg/mL
  3. Danoprevir (RG7227)
    A4024 Danoprevir (RG7227)
    Target: HCV Proteases
    Summary: HCV NS3/4A protease inhibitor
      ≥32.6 mg/mL
  4. Telaprevir (VX-950)
    A4031 Telaprevir (VX-950)
    Target: HCV NS3-4A protease
    Summary: HCV NS3-4A protease inhibitor
      ≥32.95 mg/mL
  5. VX-222 (VCH-222, Lomibuvir)
    A4032 VX-222 (VCH-222, Lomibuvir)
    Target: HCV polymerase
    Summary: NNI of HCV RNA polymerase
      ≥44.6 mg/mL
  6. Nesbuvir
    A3655 Nesbuvir
    Target: Nonstructural protein 5B (NS5B)
    Summary: NS5B polymerase inhibitor
      ≥22.3 mg/mL
  7. Simeprevir
    A3820 Simeprevir
     1 Citation
    Target: HCV Proteases
    Summary: Inhibitor of HCV NS3/4A protease
      insoluble in H2O; insoluble in EtOH; ≥18.75 mg/mL

7 Items

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