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Raf

Raf is a family of three serine/threonine-specific protein kinases that are related to retroviral oncogenes.

6 Items

per page
  1. GDC-0879
    A5071 GDC-0879
     1 Citation
    Target: Raf
    Summary: B-Raf inhibitor,potent and selective
      insoluble in EtOH; insoluble in H2O; ≥16.7 mg/mL
  2. LY3009120
    A8716 LY3009120
    Target: Raf
    Summary: pan-RAF and RAF dimer inhibitor
      insoluble in H2O; insoluble in EtOH; ≥4.25 mg/mL
  3. LGX818
    B1174 LGX818
    Target: Raf
    Summary: RAF inhibitor,potent and selective
      insoluble in EtOH; insoluble in H2O; ≥13.38 mg/mL
  4. Vemurafenib (PLX4032, RG7204)
    A3004 Vemurafenib (PLX4032, RG7204)
     9 Citation
    Target: Raf
    Summary: BRAF kinase inhibitor
      ≥24.5 mg/mL
  5. Sorafenib
    A3009 Sorafenib
     2 Citation
    Target: Raf|VEGFR
    Summary: Raf kinases and tyrosine kinases inhibitor
      ≥23.25 mg/mL
  6. PLX-4720
    A3016 PLX-4720
     1 Citation
    Target: Raf
    Summary: BRAF kinase inhibitor
      ≥20.69 mg/mL

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