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p38

p38 (p38 mitogen-activated protein kinases) are serine/threonine kinases that activated by environmental stress and proinflammatory cydtokines. They mediates cell growth, differentiation, transcrption and development.

Items 11-20 of 29

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  1. AL 8697
    B7784 AL 8697
    Target: p38
    Summary: p38α inhibitor,potent and selective
      <40.24 mg/mL
  2. SB 706504
    B4937 SB 706504
    Summary: p38 MAPK inhibitor
      <49.25 mg/mL
  3. Pexmetinib (ARRY-614)
    B6012 Pexmetinib (ARRY-614)
    Target: p38|Tie-2
    Summary: dual inhibitor of p38 MAPK and Tie2/Tek receptor tyrosine kinase
      insoluble in H2O; ≥107.6 mg/mL
  4. BMS-582949
    B6187 BMS-582949
    Summary: p38 MAPK inhibitor
      Soluble in DMSO
  5. Pamapimod (R-1503, Ro4402257)
    B6188 Pamapimod (R-1503, Ro4402257)
    Summary: p38 MAPK inhibitor
      Soluble in DMSO
  6. SB 202474
    C4949 SB 202474
    Summary: a negative control in studies of p38 inhibition
      Soluble in methanol;Soluble in DMSO
  7. BMS-582949 hydrochloride
    B7850 BMS-582949 hydrochloride
    Summary: p38 MAPK inhibitor
      ≥44.3 mg/mL
  8. RWJ 67657
    C5316 RWJ 67657
    Summary: orally active inhibitor of the MAP kinases p38α and p38β
      ≤10 mg/mL
  9. Losmapimod
    B4620 Losmapimod
     1 Citation
    Summary: p38 MAPK inhibitor, orally active
      insoluble in EtOH; insoluble in H2O; ≥19.15 mg/mL
  10. AMG 548
    B5496 AMG 548
    Summary: P38α inhibitor,potent and selective
      <49.8 mg/mL

Items 11-20 of 29

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