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EGFR

EGFR (epidermal growth factor receptor) is the cell-surface receptor of its specific ligands, including epidermal growth factor and TGFα (transforming growth factor α) and is a receptor tyrosine kinase.

Items 1-10 of 11

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  1. Gefitinib (ZD1839)
    A8219 Gefitinib (ZD1839)
     3 Citation
    Target: EGFR
    Summary: Selective EGFR inhibitor
      ≥22.34 mg/mL
  2. Afatinib (BIBW2992)
    A8247 Afatinib (BIBW2992)
     1 Citation
    Target: EGFR
    Summary: Irreversible EGFR/HER2 inhibitor
      ≥24.3 mg/mL
  3. CP-724714
    A2412 CP-724714
    Target: VEGFR|PDGFR|Bcr-Abl|Src|EGFR|c-MET|Insulin Receptors|IRG-1R
    Summary: HER2 inhibitor,potent and selective
      ≥23.5 mg/mL
  4. AC480 (BMS-599626)
    A2822 AC480 (BMS-599626)
    Target: EGFR
    Summary: HER1/2 inhibitor,selective and efficacious
      ≥28.35 mg/mL
  5. AG-1478
    A8357 AG-1478
    Target: EGFR
    Summary: EGFR inhibitor,potent and selective
      insoluble in H2O; ≥15.8 mg/mL
  6. AZD8931 (Sapitinib)
    A8375 AZD8931 (Sapitinib)
    Target: EGFR|ErbB
    Summary: ErbB inhibitor
      ≥23.7 mg/mL
  7. AZ5104
    B5836 AZ5104
    Target: EGFR
    Summary: EGFR inhibitor
      insoluble in H2O; ≥16.95 mg/mL
  8. AZD-9291
    B1104 AZD-9291
     1 Citation
    Target: EGFR
    Summary: Mutated forms EGFR inhibitor
      ≥24.98 mg/mL
  9. AG-490
    A4139 AG-490
     3 Citation
    Target: EGFR|JAK
    Summary: JAK2/EGFR inhibitor
      insoluble in H2O; ≥14.7 mg/mL
  10. CO-1686 (AVL-301)
    A3320 CO-1686 (AVL-301)
     1 Citation
    Target: EGFR
    Summary: EGFR inhibitor
      ≥27.8 mg/mL

Items 1-10 of 11

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