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Signaling Pathways

Signaling Pathways

A4330 Isotretinoin

Target: RARs

Summary: Dopamine β-hydroxylase activator

insoluble in H2O; ≥13.8 mg/mL
B4654 AM580

Target: RARs

Summary: Selective RARα agonist

insoluble in H2O; ≥14.3 mg/mL
B4702 AGN 194310
1 Citation

Target: RARs

Summary: pan-RAR antagonist

insoluble in H2O; ≥16.8 mg/mL
B7397 BMS 961

Target: RARs

Summary: Selective RARγ agonist

<39.95 mg/mL
B1175 Palovarotene

Target: RARs

Summary: Selective retinoic acid receptor gamma(RAR-γ) agonist

≥41.5 mg/mL
A1267 Adapalene

Target: RARs

Summary: RARβ and RARγ agonist

insoluble in H2O; insoluble in EtOH; ≥10.31 mg/mL
A2415 Acitretin

Target: RARs

Summary: Metabolite of etretinate

insoluble in EtOH; insoluble in H2O; ≥16.32 mg/mL