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Signaling Pathways

Signaling Pathways

B4904 ACTB-1003

Target: VEGFR|FGFR|Tie-2|RSK|p70 S6K

Summary: FGFR1 inhibitor

insoluble in H2O; ≥18.15 mg/mL
B5832 Altiratinib
1 Citation

Target: FLT3|VEGFR|Trk Receptors|c-MET|Tie-2

Summary: c-MET/TIE-2/VEGFR inhibitor

≥21.55 mg/mL
B6012 Pexmetinib (ARRY-614)

Target: p38|Tie-2

Summary: dual inhibitor of p38 MAPK and Tie2/Tek receptor tyrosine kinase

insoluble in H2O; ≥107.6 mg/mL
A5979 Tie2 kinase inhibitor

Target: Tie-2

Summary: Tie-2(Tie2 ) inhibitor

≥22 mg/mL
B1404 DCC-2036 (Rebastinib)

Target: FLT3|Bcr-Abl|Tie-2|KDR

Summary: Bcr-Abl inhibitor

≥27.7 mg/mL