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Signaling Pathways

Signaling Pathways

A5166 Ondansetron HCl

Target: 5-HT3 Receptors

Summary: 5-HT3 receptor antagonist

insoluble in EtOH; insoluble in H2O; ≥33.04 mg/mL
A8496 Paliperidone

Target: 5-HT2 Receptors|D2 Receptors|D3 Receptors|5-HT1 Receptors|Histamine H1 Receptors

Summary: Dopamine receptor antagonist

insoluble in H2O; insoluble in EtOH; ≥10.662 mg/mL
A8537 Thioridazine HCl

Target: Cytochrome P450 (CYP450)|D1 and D5 Receptors|D2 Receptors|D3 Receptors|D4 Receptors

Summary: Calcium channel protein inhibitor
B2235 Clozapine

Target: 5-HT2 Receptors|D1 and D5 Receptors|D2 Receptors|D3 Receptors|5-HT1 Receptors|D4 Receptors

Summary: 5-HT receptor antagonist

insoluble in H2O; ≥14.95 mg/mL
B2240 Olanzapine

Target: 5-HT2 Receptors|D2 Receptors

Summary: Antagonist of 5-HT2A and dopamine D2 receptors

insoluble in H2O; ≥15.6 mg/mL
B1001 Loxapine
1 Citation

Target: 5-HT2 Receptors

Summary: 5-HT receptor antagonist

≥55.6 mg/mL
B1490 Quetiapine Fumarate
1 Citation

Target: 5-HT2 Receptors|D1 and D5 Receptors|D2 Receptors|D3 Receptors|5-HT1 Receptors|5-HT7 Receptors

Summary: Dopamine receptor antagonist

insoluble in H2O; insoluble in EtOH; ≥11.03 mg/mL
B1477 Lurasidone HCl

Target: 5-HT2 Receptors|D2 Receptors|5-HT1 Receptors|5-HT7 Receptors

Summary: Dopamine D2/5-HT2A/5-HT7/5-HT1A inhibitor

insoluble in H2O; insoluble in EtOH; ≥11.11 mg/mL
A4325 PF-2545920

Target: Phosphodiesterases (PDEs)

Summary: PDE10A inhibitor,potent and selective

insoluble in H2O; ≥19.35 mg/mL
A4383 Tolcapone

Target: Catechol O-Methyltransferase (COMT)

Summary: COMT inhibitor

insoluble in H2O; ≥12 mg/mL