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Signaling Pathways

Signaling Pathways

B2151 STF-62247

Target: Autophagy

Summary: Autophagy inducer in renal cell
A4005 RO4929097
1 Citation

Summary: γ secretase inhibitor

≥23.47 mg/mL
A4111 VX-680 (MK-0457,Tozasertib)

Target: Aurora Kinases

Summary: Aurora kinase inhibitor

≥23.25 mg/mL
A8178 Panobinostat (LBH589)
10 Citation

Target: Histone Deacetylases (HDACs)

Summary: HDAC inhibitor

insoluble in H2O; insoluble in EtOH; ≥17.47 mg/mL
B1564 Ranitidine

Target: Histamine H2 Receptors

Summary: Histamine H2-receptor antagonist

≥17.54 mg/mL
B1510 Medroxyprogesterone acetate

Target: Progesterone Receptors

Summary: Steroidal progestin
B2295 Pirarubicin
1 Citation

Target: Topoisomerases

Summary: Topoisomerase II inhibitor;anthracycline antibiotic

insoluble in H2O; insoluble in EtOH; ≥7.65 mg/mL
A8255 Sunitinib malate
2 Citation

Target: VEGFR

Summary: VEGFR/PDGFRβ/ KIT/ FLT3/RET/CSF-1R inhibitor

≥26.65 mg/mL
A2251 Tivozanib (AV-951)

Target: VEGFR

Summary: VEGFR inhibitor,potent and selective

≥22.75 mg/mL
A8325 Tivantinib (ARQ 197)
2 Citation

Target: MET

Summary: C-Met inhibitor,non-ATP-competitive

≥18.47 mg/mL