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Signaling Pathways

Signaling Pathways

B4890 HPOB
1 Citation

Target: Histone Deacetylases (HDACs)

Summary: HDAC6 inhibitor, potent and selective

≥31.4 mg/mL
B4900 Indoximod (NLG-8189)

Summary: Indoleamine 2,3-dioxygenase (IDO) pathway inhibitor

insoluble in DMSO; insoluble in EtOH; ≥1.12 mg/mL
B2157 Cabazitaxel
3 Citation

Target: Microtubule/Tubulin

Summary: Microtubule associated inhibitor

≥22.3 mg/mL
B2266 LDE225 (NVP-LDE225,Erismodegib)
1 Citation

Target: Smoothened

Summary: Smoothened inhibitor,potent and selective

≥24.3 mg/mL
B2283 Niclosamide

Target: STAT

Summary: Inhibitor of the STAT3 signaling pathway
B1564 Ranitidine

Target: Histamine H2 Receptors

Summary: Histamine H2-receptor antagonist

≥17.54 mg/mL
A8182 3-Deazaneplanocin A (DZNep) hydrochloride
1 Citation

Target: EZH2

Summary: SAHH and EZH2 inhibitor

insoluble in EtOH; ≥14.94 mg/mL
A8219 Gefitinib (ZD1839)
3 Citation

Target: EGFR

Summary: Selective EGFR inhibitor

≥22.34 mg/mL
A8233 DMXAA (Vadimezan)
2 Citation

Target: DT-diaphorases

Summary: Tumnor vascular disrupting agent, apoptosis inducer

insoluble in H2O; insoluble in EtOH; ≥14.1 mg/mL
A2678 SU11274
2 Citation

Target: MET

Summary: C-Met inhibitor,potent and selective

≥28.4 mg/mL