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Signaling Pathways

Signaling Pathways

B6032 CB-5083

Target: p97

Summary: p97 inhibitor

insoluble in H2O; ≥20.65 mg/mL
A4083 Rocilinostat (ACY-1215)
1 Citation

Target: Histone Deacetylases (HDACs)

Summary: Selective HDAC6 inhibitor

≥21.675 mg/mL
A4093 ITF2357 (Givinostat)
2 Citation

Target: Histone Deacetylases (HDACs)

Summary: HDAC inhibitor

≥23.8 mg/mL
A4061 IPI-504 (Retaspimycin hydrochloride)
3 Citation

Target: HSP90

Summary: Hsp90 inhibitor,novel, potent,selective

≥26.1 mg/mL
A4065 PF-04929113 (SNX-5422)

Target: HSP90

Summary: Hsp90 inhibitor,potent and selective

≥23.85 mg/mL
A4212 Pomalidomide (CC-4047)

Summary: Immunomodulator,antumor/anti-angiogenic

insoluble in EtOH; insoluble in H2O; ≥7.5 mg/mL
A4010 Salinosporamide A (NPI-0052, Marizomib)

Target: Proteasome

Summary: 20S proteasome inhibitor

Soluble in DMSO
A2614 Bortezomib (PS-341)
24 Citation

Target: Proteasome

Summary: Proteasome Inhibitor

insoluble in EtOH; insoluble in H2O; ≥19.21 mg/mL
A1907 5-Azacytidine
6 Citation

Target: DNA Methyltransferases

Summary: DNA methyltransferase inhibitor.

insoluble in EtOH; ≥24.45 mg/mL
A1933 Carfilzomib (PR-171)
10 Citation

Target: Proteasome

Summary: Proteasome inhibitor, epoxomicin analog

≥35.99 mg/mL