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Signaling Pathways

Signaling Pathways

A4031 Telaprevir (VX-950)

Target: HCV NS3-4A protease

Summary: HCV NS3-4A protease inhibitor

≥32.95 mg/mL
A4032 VX-222 (VCH-222, Lomibuvir)

Target: HCV polymerase

Summary: NNI of HCV RNA polymerase

≥44.6 mg/mL
A3655 Nesbuvir

Target: Nonstructural protein 5B (NS5B)

Summary: NS5B polymerase inhibitor

≥22.3 mg/mL
A3820 Simeprevir
1 Citation

Target: HCV Proteases

Summary: Inhibitor of HCV NS3/4A protease

insoluble in H2O; insoluble in EtOH; ≥18.75 mg/mL