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Signaling Pathways

Signaling Pathways

B4899 BLZ945
1 Citation

Target: CSF-1R

Summary: CSF-1R kinase inhibitor

insoluble in EtOH; insoluble in H2O; ≥19.9 mg/mL
B4900 Indoximod (NLG-8189)

Summary: Indoleamine 2,3-dioxygenase (IDO) pathway inhibitor

insoluble in DMSO; insoluble in EtOH; ≥1.12 mg/mL
B2266 LDE225 (NVP-LDE225,Erismodegib)
1 Citation

Target: Smoothened

Summary: Smoothened inhibitor,potent and selective

≥24.3 mg/mL
B2194 Tolbutamide

Target: cAMP|Sulfonylurea receptors

Summary: first generation potassium channel blocker

insoluble in H2O; ≥10.05 mg/mL
A4489 TC-A 2317 hydrochloride

Target: Aurora Kinases

Summary: Aurora kinase A inhibitor,potent and selective

<39.29 mg/mL
A5112 XL147

Target: PI3K

Summary: PI3K inhibitor,selective and reversible

≥22.45 mg/mL
A5166 Ondansetron HCl

Target: 5-HT3 Receptors

Summary: 5-HT3 receptor antagonist

insoluble in EtOH; insoluble in H2O; ≥33.04 mg/mL
A8336 KU-60019
2 Citation

Target: ATM/ATR

Summary: ATM kinase inhibitor,potent and selective

≥27.4 mg/mL
B1642 WYE-125132 (WYE-132)

Target: mTOR

Summary: ATP-competitive mTOR inhibitor, highly potent

insoluble in EtOH; insoluble in H2O; ≥13 mg/mL
A3010 MK-2206 dihydrochloride
21 Citation

Target: Akt

Summary: Akt1/2/3 inhibitor

insoluble in EtOH; ≥12.01 mg/mL