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Signaling Pathways

Signaling Pathways

A3010 MK-2206 dihydrochloride
21 Citation

Target: Akt

Summary: Akt1/2/3 inhibitor

insoluble in EtOH; ≥12.01 mg/mL
A3015 BKM120
1 Citation

Target: PI3K

Summary: Inhibitor of pan-Class I PI3K

≥20.52 mg/mL
A2583 Lactacystin (Synthetic)
1 Citation

Target: Proteasome

Summary: Proteasome inhibitor

Soluble in H2O
A4049 Marimastat
1 Citation

Target: MMP

Summary: MMPs inhibitor,board spectrum

≥2.8 mg/mL
A3543 LDE225 Diphosphate

Target: Smoothened

Summary: Smo antagonist

≥27.85 mg/mL
B4899 BLZ945
1 Citation

Target: CSF-1R

Summary: CSF-1R kinase inhibitor

insoluble in EtOH; insoluble in H2O; ≥19.9 mg/mL
B4900 Indoximod (NLG-8189)

Summary: Indoleamine 2,3-dioxygenase (IDO) pathway inhibitor

insoluble in DMSO; insoluble in EtOH; ≥1.12 mg/mL
A8178 Panobinostat (LBH589)
10 Citation

Target: Histone Deacetylases (HDACs)

Summary: HDAC inhibitor

insoluble in H2O; insoluble in EtOH; ≥17.47 mg/mL
B2194 Tolbutamide

Target: cAMP|Sulfonylurea receptors

Summary: first generation potassium channel blocker

insoluble in H2O; ≥10.05 mg/mL
B2186 GSK2636771

Target: PI3K

Summary: PIK3 inhibitor

insoluble in H2O; insoluble in EtOH; ≥10.83 mg/mL