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Signaling Pathways

Signaling Pathways

A8214 AZD8055
2 Citation

Target: mTOR

Summary: MTOR inhibitor

≥23.3 mg/mL
A8551 INK 128 (MLN0128)
4 Citation

Target: mTOR

Summary: MTOR(TORC-1/-2) inhibitor,potent and selective

insoluble in H2O; ≥15.45 mg/mL
A8556 GSK2126458
1 Citation

Target: PI3K|mTOR

Summary: PI3K/mTOR inhibitor

≥25.3 mg/mL
B1642 WYE-125132 (WYE-132)

Target: mTOR

Summary: ATP-competitive mTOR inhibitor, highly potent

insoluble in EtOH; insoluble in H2O; ≥13 mg/mL
B2172 PP121

Target: mTOR|Eph Receptors|VEGFR|PDGFR|Bcr-Abl|Src|DNA-PK|P110|Hck

Summary: Dual inhibitor of tyrosine and phosphoinositide kinases
B6099 LY3023414

Target: Akt|PI3K|mTOR|DNA-PK

Summary: class I PI3K isoforms, mTOR and DNA-PK inhibitor

≥40.6 mg/mL
B1639 Ridaforolimus (Deforolimus, MK-8669)

Target: mTOR

Summary: MTOR inhibitor

≥49.5 mg/mL
B1641 WAY-600

Target: mTOR

Summary: MTOR inhibitor

≥12.38 mg/mL
A8169 Everolimus (RAD001)
8 Citation

Target: mTOR

Summary: MTOR inhibitor

≥47.91 mg/mL
A3927 VS-5584 (SB2343)

Target: PI3K|mTOR

Summary: MTOR/P13K inhibitor,potent and selective

insoluble in H2O; ≥17.7 mg/mL