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Signaling Pathways

Signaling Pathways

A4010 Salinosporamide A (NPI-0052, Marizomib)

Target: Proteasome

Summary: 20S proteasome inhibitor

Soluble in DMSO
A8202 Abiraterone acetate

Target: Cytochrome P450 (CYP450)

Summary: Cytochrome p450 17a1 inhibitor

insoluble in H2O; ≥11.22 mg/mL
A4300 GW9662
1 Citation

Summary: PPARγ antagonist

insoluble in H2O; ≥13.75 mg/mL
A8322 Neratinib (HKI-272)
1 Citation

Target: EGFR

Summary: HER2/EGFR inhibitor,potent and irreversible

insoluble in H2O; ≥13.93 mg/mL