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Signaling Pathways

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  1. AS-605240
    A5176 AS-605240
    Target: PI3K
    Summary: Potent and selective PI 3-Kγ inhibitor
      insoluble in H2O; insoluble in EtOH; ≥4.28 mg/mL
  2. MEK162 (ARRY-162, ARRY-438162)
    A1947 MEK162 (ARRY-162, ARRY-438162)
    Target: MEK
    Summary: MEK1/2 inhibitor,potent and selective
      insoluble in H2O; insoluble in EtOH; insoluble in DMSO
  3. R788 disodium
    A8332 R788 disodium
    Target: Syk
    Summary: Syk inhibitor,ATP competitive and potent
      ≥62.4 mg/mL
  4. VX-745
    A8686 VX-745
    Target: p38
    Summary: P38α inhibitor,highly potent and selective
      ≥21.8 mg/mL
  5. Fostamatinib (R788)
    B2284 Fostamatinib (R788)
    Target: Syk
    Summary: Spleen tyrosine kinase (Syk) inhibitor
      insoluble in H2O; ≥100.4 mg/mL

Items 11-15 of 15

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