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Signaling Pathways

Signaling Pathways

A3342 D4476
1 Citation

Target: CK1

Summary: CK1/ALK5 inhibitor,specific and cell permeable

insoluble in H2O; ≥19.9 mg/mL
A3543 LDE225 Diphosphate

Target: Smoothened

Summary: Smo antagonist

≥27.85 mg/mL
A3692 OTX-015
3 Citation

Target: Bromodomains

Summary: BRD inhibitor

≥24.6 mg/mL
A3843 SU 5402

Target: VEGFR|PDGFR|FGFR

Summary: VEGFR2/FGFR/PDGFR/EGFR inhibitor

insoluble in EtOH; insoluble in H2O; ≥14.8 mg/mL
B2266 LDE225 (NVP-LDE225,Erismodegib)
1 Citation

Target: Smoothened

Summary: Smoothened inhibitor,potent and selective

≥24.3 mg/mL
B1943 Fenofibrate
1 Citation

Summary: PPARα agonist

insoluble in H2O; ≥12.75 mg/mL
A8178 Panobinostat (LBH589)
10 Citation

Target: Histone Deacetylases (HDACs)

Summary: HDAC inhibitor

insoluble in H2O; insoluble in EtOH; ≥17.47 mg/mL
B5624 STF 083010

Target: Inositol-requiring enzyme 1 (IRE1)

Summary: IRE1α endonuclease inhibitor

≥31.7 mg/mL
B4904 ACTB-1003

Target: VEGFR|FGFR|Tie-2|RSK|p70 S6K

Summary: FGFR1 inhibitor

insoluble in H2O; ≥18.15 mg/mL
B5638 ACHP

Summary: IκB kinase inhibitor

<7.29 mg/mL