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Signaling Pathways

Items 1-10 of 114

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  1. Stiripentol
    A8704 Stiripentol
    Target: Lactate Dehydrogenases (LDH)
    Summary: An LDH inhibitor
  2. Isosafrole
    A8703 Isosafrole
    Target: Lactate Dehydrogenases (LDH)
    Summary: A stiripentol analog, a potent LDH inhibitor.
  3. Dutasteride
    A1659 Dutasteride
    Target: 5-alpha Reductases
    Summary: 5-alpha-reductase inhibitor
      ≥26.43 mg/mL
  4. 17-DMAG (Alvespimycin) HCl
    A2213 17-DMAG (Alvespimycin) HCl
     1 Citation
    Target: HSP90
    Summary: Hsp90 inhibitor
      ≥26.2 mg/mL
  5. Posaconazole
    A1718 Posaconazole
    Target: Cytochrome P450 (CYP450)|sterol demethylase
    Summary: Sterol C14ɑ demethylase inhibitor
      ≥35.04 mg/mL
  6. MOG (35-55)
    A8306 MOG (35-55)
     1 Citation
    Summary: Minor component of CNS myelin
      ≥32.25 mg/mL
  7. Canagliflozin
    A8333 Canagliflozin
     1 Citation
    Target: SGLT
    Summary: SGLT2 inhibitor,potent and selective
      ≥22.25 mg/mL
  8. Ezetimibe
    A8430 Ezetimibe
    Target: Cholesterol absorption
    Summary: Cholesterol transport inhibitor
      ≥20.45 mg/mL
  9. Pitavastatin Calcium
    A8504 Pitavastatin Calcium
     1 Citation
    Target: HMG-CoA Reductases
    Summary: Enzyme HMGCR inhibitor
      ≥34.85 mg/mL
  10. Simvastatin (Zocor)
    A8522 Simvastatin (Zocor)
    Target: HMG-CoA Reductases
    Summary: HMGCR (HMG-CoA reductase) inhibitor

Items 1-10 of 114

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Category
  1. PPAR13item
  2. 5-alpha Reductase1 item
  3. 5-Lipoxygenase1 item
  4. Aminopeptidase1 item
  5. C14ɑ demethylase1 item
  6. Carbonic Anhydrase3item
  7. CETP2item
  8. Cholesterol absorption1 item
  9. CYP3A/CYP4504item
  10. Dehydrogenase6item
  11. DHFR2item
  12. DGAT1 item
  13. Dopamine β-hydroxylase4item
  14. FAAH1 item
  15. Factor Xa1 item
  16. Ferroptosis1 item
  17. Folate Analogue1 item
  18. Glucokinase1 item
  19. HMG-CoA Reductase7item
  20. HSP12item
  21. IDO4item
  22. KRAS-PDEδ1 item
  23. Lipid Metabolism2item
  24. Neuronal Metabolism1 item
  25. Oxidative Phosphorylation1 item
  26. P4503item
  27. PDE19item
  28. Phospholipase2item
  29. Saccharometabolism1 item
  30. SCD1 item
  31. SGLT1 item
  32. TPH3item
  33. Transferase8item
  34. monooxygenase1 item
  35. Hydrolase2item
Specificity
  1. Selective75item
  2. Non-Selective1 item
Reversibility
  1. Reversible1 item
  2. Irreversible5item
Target
  1. Acyl coenzyme A: cholesterol acyltransferases1 item
  2. Factor Xa1 item
  3. Phosphodiesterases (PDEs)17item
  4. Thymidylate Synthase1 item
  5. Kynurenine-3-monooxygenase1 item
  6. RARs1 item
  7. Aminopeptidases1 item
  8. Stearoyl-CoA 9-desaturase (SCD-1)2item
  9. HSP909item
  10. Cytochrome P450 (CYP450)7item
  11. HMG-CoA Reductases6item
  12. SGLT1 item
  13. DGAT2item
  14. Insulin and Insulin-like Receptors1 item
  15. Pyruvate dehydrogenases (PDH)1 item
  16. CETP2item
  17. Lactate Dehydrogenases (LDH)2item
  18. Fatty-acid-binding proteins (FABPs)1 item
  19. Folate Analogue1 item
  20. Nampt1 item
  21. Carbonic Anhydrases3item
  22. Aldehyde Dehydrogenases2item
  23. Phospholipases1 item
  24. Inward Rectifier Potassium (Kir) Channels1 item
  25. Catechol O-Methyltransferase (COMT)1 item
  26. Hydroxylases1 item
  27. FPTase1 item
  28. Tryptophan hydroxylases (TPH)2item
  29. sodium channel1 item
  30. PPAR4item
  31. Ftase1 item
  32. PC-PLC1 item
  33. GK1 item
  34. HMGCR1 item
  35. adrenergic receptor1 item
  36. sterol demethylase1 item
  37. GAPDH1 item
  38. complex I of the mitochondrial electron transport chain1 item
  39. potassium channel1 item
  40. calcium channel1 item
  41. FAAH1 item
  42. carnitine reabsorption1 item
  43. 5-alpha Reductases1 item
  44. DHFR1 item
  45. GARFT1 item
  46. glutathione peroxidase 41 item
  47. S-adenosylhomocysteine hydrolase1 item
  48. IDO1 item
  49. Tph1 item
  50. epoxide hydrolase1 item
  51. Cholesterol absorption1 item
  52. Glycogen Phosphorylases1 item
Related Disease
  1. Acne1 item
  2. Acute Kidney Injury1 item
  3. Acute Myeloid Leukemia2item
  4. Bladder Cancer1 item
  5. Bladder Carcinoma1 item
  6. Brain Injuries Studies1 item
  7. Breast Cancer9item
  8. Cancer35item
  9. Cervical Cancer1 item
  10. Chronic Lymphocytic Leukemia1 item
  11. Cocaine-Related Disorders2item
  12. Colon Cancer1 item
  13. Diabetes4item
  14. Dyslipidemia1 item
  15. Epilepsy2item
  16. Erectile Dysfunction4item
  17. Fungi1 item
  18. Glioblastoma1 item
  19. Glioma1 item
  20. Hepatic Cancer1 item
  21. HIV Infections1 item
  22. Hypercholesterolemia3item
  23. Inflammation1 item
  24. Inflammatory Diseases2item
  25. Kidney Injury Studies1 item
  26. Leukemia2item
  27. Lung Cancer5item
  28. Lymphoma3item
  29. Melanoma8item
  30. Multiple Myeloma3item
  31. Neuroblastoma3item
  32. Neurocognitive Disorders1 item
  33. Non-small Cell Lung Cancer2item
  34. Obsessive-Compulsive Disorder1 item
  35. Osteoporosis1 item
  36. Pancreatic Cancer2item
  37. Pancreatic Carcinoma1 item
  38. Prostate Cancer7item
  39. Psoriasis3item
  40. Psoriasis Vulgaris1 item
  41. Pulmonary Arterial Hypertension1 item
  42. Rheumatoid Arthritis2item
  43. Schizophrenia2item
  44. Type 2 Diabetes5item