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Signaling Pathways

Signaling Pathways

B4900 Indoximod (NLG-8189)

Summary: Indoleamine 2,3-dioxygenase (IDO) pathway inhibitor

insoluble in DMSO; insoluble in EtOH; ≥1.12 mg/mL
A4061 IPI-504 (Retaspimycin hydrochloride)
3 Citation

Target: HSP90

Summary: Hsp90 inhibitor,novel, potent,selective

≥26.1 mg/mL
A4064 NVP-BEP800

Target: HSP90

Summary: Oral Hsp90β inhibitor, novel, fully synthetic
A4330 Isotretinoin

Target: RARs

Summary: Dopamine β-hydroxylase activator

insoluble in H2O; ≥13.8 mg/mL
A4347 Methotrexate
2 Citation

Target: Folate Analogue

Summary: Folate antagonist,inhibits DFHR

≥21.55 mg/mL