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Signaling Pathways

Signaling Pathways

B3272 Inauhzin

Target: Sir2-like Family Deacetylases (Sirtuins)

Summary: SIRT1 inhibitor

≥23.5 mg/mL
A4090 JNJ-26481585
3 Citation

Target: Histone Deacetylases (HDACs)

Summary: Potent HDAC inhibitor

insoluble in H2O; insoluble in EtOH; ≥19.2 mg/mL
A4112 Barasertib (AZD1152-HQPA)
3 Citation

Target: Aurora Kinases

Summary: Aurora Kinase B inhibitor, Potent and selective

≥25.4 mg/mL
A4127 GSK1070916

Target: Aurora Kinases

Summary: Aurora B/C inhibitor

≥25.4 mg/mL
A4128 PF-03814735

Target: Aurora Kinases

Summary: Aurora A/B inhibitor

Soluble in DMSO
A1913 RG 108
3 Citation

Target: DNA Methyltransferases

Summary: DNA methyltransferase inhibitor

insoluble in H2O; ≥16.7 mg/mL
A3214 AZD1152
1 Citation

Target: Aurora Kinases

Summary: Aurora B kinase inhibitor,highly potent and selective

insoluble in H2O; insoluble in EtOH; ≥5.88 mg/mL
A8171 Entinostat (MS-275,SNDX-275)
2 Citation

Target: Histone Deacetylases (HDACs)

Summary: HDAC1 and HDAC3 inhibitor

insoluble in H2O; ≥18.8 mg/mL
A8176 Apicidin
2 Citation

Target: Histone Deacetylases (HDACs)

Summary: Potent HDAC inhibitor

soluble in DMSO or ethanol
A4512 Cucurbitacin I

Target: STAT|JAK

Summary: STAT3/JAK2 signaling inhibitor

≥22.45 mg/mL