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Signaling Pathways

Signaling Pathways

A4186 Bromosporine
1 Citation

Target: Bromodomains

Summary: Bromodomain inhibitor,non-selective

≥40.4 mg/mL
A4152 BMS-911543

Target: JAK

Summary: JAK2 inhibitor,selective small molecule

≥43.3 mg/mL
A1907 5-Azacytidine
6 Citation

Target: DNA Methyltransferases

Summary: DNA methyltransferase inhibitor.

insoluble in EtOH; ≥24.45 mg/mL
A1912 Lomeguatrib

Target: O6-methylguanine-DNA-methyl-transferase (MGMT)

Summary: MGMT inhibitor

≥50 mg/mL
A1913 RG 108
3 Citation

Target: DNA Methyltransferases

Summary: DNA methyltransferase inhibitor

insoluble in H2O; ≥16.7 mg/mL
A1915 Zebularine
1 Citation

Target: DNA Methyltransferases|Cytidine deaminases

Summary: DNA methylation inhibitor

insoluble in EtOH; ≥50.7 mg/mL
A3214 AZD1152
1 Citation

Target: Aurora Kinases

Summary: Aurora B kinase inhibitor,highly potent and selective

insoluble in H2O; insoluble in EtOH; ≥5.88 mg/mL
A3556 LKB1 (AAK1 dual inhibitor)

Target: Pim

Summary: Pim-1 kinase inhibitor

insoluble in EtOH; insoluble in H2O; ≥34.8 mg/mL
B4890 HPOB
1 Citation

Target: Histone Deacetylases (HDACs)

Summary: HDAC6 inhibitor, potent and selective

≥31.4 mg/mL
B4894 SP2509

Target: Histone Demethylases

Summary: Demethylase 1 (LSD1) antagonist, novel Lysine-specific

insoluble in H2O; insoluble in EtOH; ≥19.45 mg/mL