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Signaling Pathways

Signaling Pathways

A8513 Riluzole

Target: Voltage-gated Sodium (NaV) Channels|glutamate release

Summary: Sodium channel protein inhibitor

≥23.4 mg/mL
B4798 Procainamide HCl

Target: DNA Methyltransferases

Summary: sodium channel blocker

≥13.65 mg/mL
B5895 CARIPORIDE

Target: NHE

Summary: Potent NHE inhibitor

insoluble in H2O; ≥12.05 mg/mL
B2249 Lamotrigine
1 Citation

Target: 5-HT receptors|sodium channel

Summary: 5-HT inhibitor， sodium channel blocker

insoluble in H2O; ≥12.3 mg/mL
B2274 Proparacaine HCl

Target: Voltage-gated Sodium (NaV) Channels

Summary: voltage-gated sodium channels antagonist

insoluble in EtOH; ≥14.9 mg/mL
B2278 Ibutilide Fumarate

Target: Voltage-gated Potassium (KV) Channels|Voltage-gated Calcium Channels (CaV)|sodium channel

Summary: Class III antiarrhythmic agent

≥25.6 mg/mL
B2272 Phenytoin sodium

Target: Voltage-gated Sodium (NaV) Channels

Summary: Sodium channel stabilizer

insoluble in H2O; insoluble in EtOH; ≥11.55 mg/mL
B1420 Bupivacaine HCl

Target: Voltage-gated Sodium (NaV) Channels

Summary: Anaesthetic drug

≥10.25 mg/mL
B5515 ProTx II

Target: Voltage-gated Sodium (NaV) Channels

Summary: NaV1.7 channel blocker

Soluble to 1 mg/mL
B2277 A-803467

Target: Voltage-gated Sodium (NaV) Channels

Summary: NaV1.8 channel blocker,potent and selective

insoluble in H2O; ≥13.95 mg/mL