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Signaling Pathways

Signaling Pathways

B1206 Pizotifen

Target: 5-HT2 Receptors

Summary: Highly selective 5-HT receptor blocking agent

insoluble in H2O; ≥14.77 mg/mL
B2007 Pizotifen Malate

Target: 5-HT2 Receptors|D2 Receptors

Summary: 5-HT receptor antagonist

≥21.48 mg/mL
B2251 Naratriptan

Target: 5-HT1 Receptor

Summary: selective 5-HT1 receptor subtype agonist

insoluble in H2O; ≥61.1 mg/mL
B2231 Amitriptyline HCl

Target: Trk Receptors|5-HT2 Receptors|Norepinephrine transporter|5-HT Transporters

Summary: Serotonin /norepinephrine receptor/5-HT4/5-HT2 inhibitor

≥15.69 mg/mL
B2236 Desvenlafaxine

Target: 5-HT Transporters|Norepinephrine transporters

Summary: serotonin (5-HT) and norepinephrine (NE) reuptake inhibitor

insoluble in EtOH; ≥13.2 mg/mL
B2241 Ondansetron

Target: 5-HT3 Receptors

Summary: serotonin 5-HT3 receptor antagonist

insoluble in EtOH; insoluble in H2O; ≥7.33 mg/mL
B2248 Ketanserin

Target: 5-HT2 Receptors

Summary: specific 5-HT2A serotonin receptor antagonist

≥39.5 mg/mL
B7531 WAY 208466 dihydrochloride

Target: 5-HT6 Receptor

Summary: 5-HT6 agonist

Soluble in DMSO
B6347 Methylergometrine maleate

Target: 5-HT1 Receptor|5-HT2 Receptor

Summary: 5-HT1/5-HT2 receptor antagonist

Soluble to 25 mM in H2O
B6574 BW 723C86 hydrochloride

Target: 5-HT2 Receptors

Summary: 5-HT2B agonist

Soluble in DMSO