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Signaling Pathways

Signaling Pathways

A3008 Y-27632 dihydrochloride
19 Citation

Target: ROCK

Summary: ROCK1 inhibitor

≥111.2 mg/mL
A3478 Hydroxyfasudil

Target: ROCK|Rho-kinase

Summary: Rho-kinase inhibitor and vasodilator

Soluble in DMSO
A3771 RKI-1447

Target: ROCK

Summary: Potent ROCK1/ROCK2 inhibitor

insoluble in H2O; ≥16.3 mg/mL
B3523 Fasudil

Target: ROCK|PKC|PKG|PKA|Myosin light chain kinases (MLCKs)

Summary: calcium antagonist

Soluble in DMSO
A5506 Thiazovivin

Target: ROCK

Summary: ROCK inhibitor

≥15.55 mg/mL