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Signaling Pathways

Signaling Pathways

A4112 Barasertib (AZD1152-HQPA)
3 Citation

Target: Aurora Kinases

Summary: Aurora Kinase B inhibitor, Potent and selective

≥25.4 mg/mL
A4127 GSK1070916

Target: Aurora Kinases

Summary: Aurora B/C inhibitor

≥25.4 mg/mL
A4128 PF-03814735

Target: Aurora Kinases

Summary: Aurora A/B inhibitor

Soluble in DMSO
A3214 AZD1152
1 Citation

Target: Aurora Kinases

Summary: Aurora B kinase inhibitor,highly potent and selective

insoluble in H2O; insoluble in EtOH; ≥5.88 mg/mL
A3716 PF-3758309
1 Citation

Target: PAK

Summary: PAK4 inhibitor

≥24.53 mg/mL
A1493 ABT-751 (E7010)
1 Citation

Target: Microtubules/Tubulins

Summary: Inhibitor of microtubule polymerization,antimitotic

insoluble in H2O; ≥18.55 mg/mL
A5459 PHA-793887
1 Citation

Target: Cyclin-Dependent Kinases

Summary: Pan-Cdk inhibitor

insoluble in H2O; ≥18.05 mg/mL
B3277 AMG 925

Target: Cyclin-Dependent Kinases|FLT3

Summary: FLT3/CDK4 inhibitor,potent and selective

insoluble in DMSO; insoluble in H2O; insoluble in EtOH