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Signaling Pathways

Signaling Pathways

A8717 THZ2
1 Citation

Target: Cyclin-Dependent Kinases

Summary: CDK7 inhibitor

≥28.3 mg/mL
A4489 TC-A 2317 hydrochloride

Target: Aurora Kinases

Summary: Aurora kinase A inhibitor,potent and selective

<39.29 mg/mL
A3965 BI 2536
1 Citation

Target: PLK|Bromodomain-containing proteins(BRDs)

Summary: Plk1 inhibitor,potent and ATP-competitive

insoluble in H2O; ≥13.04 mg/mL
A1765 Vincristine sulfate

Target: Microtubule/Tubulin

Summary: Microtubule disrupter,antitumor agent

≥46.15 mg/mL
A1493 ABT-751 (E7010)
1 Citation

Target: Microtubules/Tubulins

Summary: Inhibitor of microtubule polymerization,antimitotic

insoluble in H2O; ≥18.55 mg/mL
A1980 SNS-032 (BMS-387032)
2 Citation

Target: Cyclin-Dependent Kinases

Summary: CDK inhibitor

insoluble in H2O; ≥19.05 mg/mL
A1630 Epothilone B (EPO906, Patupilone)

Target: Microtubules/Tubulins

Summary: Microtubule stabilizing macrolide

≥25.4 mg/mL
A1404 Rigosertib sodium salt
1 Citation

Target: PLK

Summary: Plk1 inhibitor

≥23.65 mg/mL
A1352 Zoledronic Acid

Target: Farnesyl Diphosphate Synthases

Summary: Potent nitrogen-containing bisphosphonates

insoluble in DMSO; insoluble in H2O; insoluble in EtOH
A5343 Ispinesib (SB-715992)

Target: Ksp

Summary: Kinesin spindle protein (KSP)inhibitor

≥25.85 mg/mL