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Signaling Pathways

Signaling Pathways

B1114 T 705

Target: RNA Polymerases

Summary: Potent and selective RNA-dependent RNA polymerase inhibitor

≥2.9 mg/mL
A8189 PSI-6206
3 Citation

Target: HCV polymerase

Summary: Inhibitor of HCV RNA polymerase,potent and selective

≥13.1 mg/mL
A4031 Telaprevir (VX-950)

Target: HCV NS3-4A protease

Summary: HCV NS3-4A protease inhibitor

≥32.95 mg/mL
A4032 VX-222 (VCH-222, Lomibuvir)

Target: HCV polymerase

Summary: NNI of HCV RNA polymerase

≥44.6 mg/mL
A3655 Nesbuvir

Target: Nonstructural protein 5B (NS5B)

Summary: NS5B polymerase inhibitor

≥22.3 mg/mL