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Signaling Pathways

Signaling Pathways

A8488 NVP-BGT226

Target: PI3K|mTOR

Summary: PI3K/mTOR inhibitor,selective and novel

insoluble in EtOH; insoluble in H2O; ≥16.28 mg/mL
A8499 PF-04691502

Target: Akt|PI3K|mTOR

Summary: PI3K/mTOR (FRAP) inhibitor

insoluble in H2O; insoluble in EtOH; ≥10.63 mg/mL
B2172 PP121

Target: mTOR|Eph Receptors|VEGFR|PDGFR|Bcr-Abl|Src|DNA-PK|P110|Hck

Summary: Dual inhibitor of tyrosine and phosphoinositide kinases
B2176 GSK1059615

Target: PI3K|mTOR

Summary: PI3K and mTOR inhibitor,potent and reversible

insoluble in EtOH; insoluble in H2O; ≥8.33 mg/mL
B6099 LY3023414

Target: Akt|PI3K|mTOR|DNA-PK

Summary: class I PI3K isoforms, mTOR and DNA-PK inhibitor

≥40.6 mg/mL
A3724 PI-103 Hydrochloride

Target: PI3K|mTOR|DNA-PK

Summary: DNA-PK/PI 3-kinase/mTOR inhibitor

insoluble in H2O; insoluble in EtOH; ≥19.25 mg/mL
A3927 VS-5584 (SB2343)

Target: PI3K|mTOR

Summary: MTOR/P13K inhibitor,potent and selective

insoluble in H2O; ≥17.7 mg/mL