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Signaling Pathways

Signaling Pathways

B4660 PI-3065

Target: PI3K

Summary: P110δkinase inhibitor

≥22.7 mg/mL
A3015 BKM120
1 Citation

Target: PI3K

Summary: Inhibitor of pan-Class I PI3K

≥20.52 mg/mL
A4097 CUDC-907

Target: Histone Deacetylases (HDACs)|PI3K

Summary: Potent PI3K/HDAC inhibitor

≥25.45 mg/mL
A3724 PI-103 Hydrochloride

Target: PI3K|mTOR|DNA-PK

Summary: DNA-PK/PI 3-kinase/mTOR inhibitor

insoluble in H2O; insoluble in EtOH; ≥19.25 mg/mL
A3927 VS-5584 (SB2343)

Target: PI3K|mTOR

Summary: MTOR/P13K inhibitor,potent and selective

insoluble in H2O; ≥17.7 mg/mL
B1047 GDC-0032

Target: PI3K

Summary: PI3Kα inhibitor

≥23.05 mg/mL
B2186 GSK2636771

Target: PI3K

Summary: PIK3 inhibitor

insoluble in H2O; insoluble in EtOH; ≥10.83 mg/mL
B2178 BAY 80-6946 (Copanlisib)
1 Citation

Target: PI3K

Summary: PI3K inhibitor

insoluble in DMSO; insoluble in H2O; insoluble in EtOH
B2180 AS-252424

Target: Akt|PI3K

Summary: PI3Kγ inhibitor,novel and potent

insoluble in EtOH; insoluble in H2O; ≥30.5 mg/mL
B4492 HS-173

Target: PI3K

Summary: novel PI3K inhibitor

≥21.1 mg/mL