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Signaling Pathways

Signaling Pathways

A5078 KU-0063794

Target: mTOR

Summary: MTORC1 and mTORC2 inhibitor

insoluble in H2O; insoluble in EtOH; ≥11.65 mg/mL
A8214 AZD8055
2 Citation

Target: mTOR

Summary: MTOR inhibitor

≥23.3 mg/mL
A8312 Torin 1
7 Citation

Target: mTOR

Summary: MTOR inhibitor,potent and selective
A8318 PP242

Target: mTOR

Summary: MTOR inhibitor, selective and ATP-competitive
A8488 NVP-BGT226

Target: PI3K|mTOR

Summary: PI3K/mTOR inhibitor,selective and novel

insoluble in EtOH; insoluble in H2O; ≥16.28 mg/mL
A8499 PF-04691502

Target: Akt|PI3K|mTOR

Summary: PI3K/mTOR (FRAP) inhibitor

insoluble in H2O; insoluble in EtOH; ≥10.63 mg/mL
A8551 INK 128 (MLN0128)
4 Citation

Target: mTOR

Summary: MTOR(TORC-1/-2) inhibitor,potent and selective

insoluble in H2O; ≥15.45 mg/mL
A8556 GSK2126458
1 Citation

Target: PI3K|mTOR

Summary: PI3K/mTOR inhibitor

≥25.3 mg/mL
A8626 ETP-46464

Target: PI3K|mTOR|DNA-PK|ATM/ATR

Summary: ATR inhibitor,potent and selective

≥16.13 mg/mL
A8764 Rapalink-1

Target: mTOR

Summary: third-generation mTOR inhibitor

≥178.4 mg/mL