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Signaling Pathways

Signaling Pathways

A1769 KU-0060648
1 Citation

Target: PI3K|DNA-PK

Summary: Dual DNA-PK/PI3-K inhibitor, ATP-competitive
A8315 NU7441 (KU-57788)
4 Citation

Target: PI3K|DNA-PK

Summary: DNA-PK inhibitor

insoluble in EtOH; insoluble in H2O; ≥4.13 mg/mL
A8626 ETP-46464

Target: PI3K|mTOR|DNA-PK|ATM/ATR

Summary: ATR inhibitor,potent and selective

≥16.13 mg/mL
A8649 NU 7026

Target: PI3K|DNA-PK|ATM

Summary: DNPK inhibitor,ATP-competitive and potent

insoluble in EtOH; insoluble in DMSO; insoluble in H2O
B2172 PP121

Target: mTOR|Eph Receptors|VEGFR|PDGFR|Bcr-Abl|Src|DNA-PK|P110|Hck

Summary: Dual inhibitor of tyrosine and phosphoinositide kinases
B1640 Torin 2
1 Citation

Target: mTOR|DNA-PK|ATM/ATR

Summary: MTOR inhibitor,highly potent and selective

≥21.6 mg/mL
B6099 LY3023414

Target: Akt|PI3K|mTOR|DNA-PK

Summary: class I PI3K isoforms, mTOR and DNA-PK inhibitor

≥40.6 mg/mL
A3724 PI-103 Hydrochloride

Target: PI3K|mTOR|DNA-PK

Summary: DNA-PK/PI 3-kinase/mTOR inhibitor

insoluble in H2O; insoluble in EtOH; ≥19.25 mg/mL