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Signaling Pathways

Signaling Pathways

A8346 BYL-719
1 Citation

Target: PI3K

Summary: Selective PI3Kα inhibitor

≥22.07 mg/mL
B1642 WYE-125132 (WYE-132)

Target: mTOR

Summary: ATP-competitive mTOR inhibitor, highly potent

insoluble in EtOH; insoluble in H2O; ≥13 mg/mL
A8169 Everolimus (RAD001)
8 Citation

Target: mTOR

Summary: MTOR inhibitor

≥47.91 mg/mL
A3010 MK-2206 dihydrochloride
21 Citation

Target: Akt

Summary: Akt1/2/3 inhibitor

insoluble in EtOH; ≥12.01 mg/mL